Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SCN1A | P35498 | 4/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 4/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17386156 | 0.90 | ALDH1A1 (0.52) | ALDH1A1LMNAKMT2ASCN1ASCN2A | |
| SCHEMBL10360804 | 0.85 | ALDH1A1 (0.77) | ALDH1A1LMNAKMT2ATSHRHIF1A | |
| SCHEMBL4068457 | 0.84 | ALDH1A1 (0.66) | ALDH1A1LMNAKMT2ASCN1ASCN2A | |
| SCHEMBL31123666 | 0.84 | ALDH1A1 (0.66) | ALDH1A1LMNAKMT2ASCN1ASCN2A | |
| SCHEMBL17429662 | 0.83 | ALDH1A1 (0.54) | ALDH1A1LMNAKMT2ATSHRHIF1A | |
| SCHEMBL17385867 | 0.83 | ALDH1A1 (0.50) | ALDH1A1LMNAKMT2ATSHRHIF1A | |
| SCHEMBL16672908 | 0.81 | ALDH1A1 (0.66) | ALDH1A1LMNAKMT2ATSHRHIF1A | |
| SCHEMBL993441 | 0.79 | ALDH1A1 (0.59) | ALDH1A1LMNAKMT2ASCN1ASCN2A | |
| SCHEMBL31123664 | 0.78 | GAA (0.57) | ALDH1A1LMNAKMT2APOLB | |
| SCHEMBL4401163 | 0.77 | ALDH1A1 (0.54) | ALDH1A1LMNAKMT2ASCN1ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9643946-B2 | Tricyclic compound and use thereof | SK CHEMICALS CO., LTD. (KR) | 2017-05-09 | — | — | US | disclosed |
| US-20160009677-A1 | TRICYCLIC COMPOUND AND USE THEREOF | SK CHEMICALS CO., LTD. (KR) | 2016-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160009677-A1 | TRICYCLIC COMPOUND AND USE THEREOF | GPR65, GPR119, GPR35 | ALDH1A1 2066/4885LMNA 2845/4885KMT2A 4155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.