Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PTGFR | P43088 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12549187 | 0.89 | LMNA (0.41) | LMNAPKMHSD17B10L3MBTL1MAOB | |
| SCHEMBL3157069 | 0.88 | L3MBTL1 (0.43) | LMNAPKMHSD17B10L3MBTL1MAOB | |
| SCHEMBL3157056 | 0.88 | L3MBTL1 (0.43) | LMNAPKMHSD17B10L3MBTL1MAOB | |
| SCHEMBL3149002 | 0.86 | LMNA (0.42) | LMNAPKMHSD17B10L3MBTL1MAOB | |
| SCHEMBL16414504 | 0.86 | ALDH1A1 (0.44) | LMNAPKMHSD17B10L3MBTL1MAOB | |
| SCHEMBL16415172 | 0.86 | ALDH1A1 (0.44) | LMNAPKMHSD17B10L3MBTL1MAOB | |
| SCHEMBL817473 | 0.86 | LMNA (0.42) | LMNAPKMHSD17B10L3MBTL1MAOB | |
| SCHEMBL15272358 | 0.86 | ALDH1A1 (0.44) | LMNAPKMHSD17B10L3MBTL1MAOB | |
| SCHEMBL17421972 | 0.85 | MAOB (0.40) | LMNAPKMHSD17B10L3MBTL1MAOB | |
| SCHEMBL17421973 | 0.85 | MAOB (0.40) | LMNAPKMHSD17B10L3MBTL1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016005943-A1 | METAL-CATALYZED ASYMMETRIC 1,4-CONJUGATE ADDITION OF VINYLBORON COMPOUNDS TO 2-SUBSTITUTED-4-OXY- CYCLOPENT-2-EN-L-ONES YIELDING PROSTAGLANDINS AND PROSTAGLANDIN ANALOGS | SCINOPHARM TAIWAN, LTD. (TW) | 2016-01-14 | — | — | WO | disclosed |