Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL817473 | 1.00 | LMNA (0.42) | LMNAPKMHSD17B10L3MBTL1MAOB | |
| SCHEMBL15272358 | 0.88 | ALDH1A1 (0.44) | LMNAPKMHSD17B10L3MBTL1MAOB | |
| SCHEMBL16414504 | 0.88 | ALDH1A1 (0.44) | LMNAPKMHSD17B10L3MBTL1MAOB | |
| SCHEMBL16415172 | 0.88 | ALDH1A1 (0.44) | LMNAPKMHSD17B10L3MBTL1MAOB | |
| SCHEMBL12549187 | 0.87 | LMNA (0.41) | LMNAPKMHSD17B10L3MBTL1MAOB | |
| SCHEMBL3157056 | 0.86 | L3MBTL1 (0.43) | LMNAPKMHSD17B10L3MBTL1MAOB | |
| SCHEMBL3157069 | 0.86 | L3MBTL1 (0.43) | LMNAPKMHSD17B10L3MBTL1MAOB | |
| SCHEMBL17429970 | 0.86 | LMNA (0.40) | LMNAPKMHSD17B10L3MBTL1MAOB | |
| SCHEMBL18022070 | 0.84 | ADRB2 (0.41) | HSD17B10L3MBTL1POLBALDH1A1ALOX15 | |
| SCHEMBL19750656 | 0.84 | LMNA (0.44) | LMNAPKMHSD17B10L3MBTL1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169467-B1 | PROCESS FOR THE PREPARATION OF PROSTAGLANDIN PRECURSORS | CHIROTECH TECHNOLOGY LTD (GB) | 2010-02-17 | — | — | EP | disclosed |
| EP-1169467-A1 | PROCESS FOR THE PREPARATION OF PROSTAGLANDIN PRECURSORS | Chirotech Technology Limited (GB) | 2002-01-09 | — | — | EP | disclosed |
| US-20010009770-A1 | Process for the preparation of prostaglandin precursors | FOX MARTIN EDWARD (GB) | 2001-07-26 | — | — | US | disclosed |
| US-6214611-B1 | PREPARATION OF A PROPARGYLIC ALCOHOL ENRICHED IN (R)-ENANTIOMER BY ESTERIFICATION OF RACEMIC ALCOHOL USING ACYL DONOR AND ENZYME, REMOVAL OF UNTREATED (S)-ALCOHOL, AND ENANTIOSELECTIVE HYDROLYSIS OF (R)-ESTER USING SECOND ENZYME | CHIROTECH TECHNOLOGY LIMITED (GB) | 2001-04-10 | — | — | US | disclosed |
| WO-2000061777-A1 | PROCESS FOR THE PREPARATION OF PROSTAGLANDIN PRECURSORS | CHIROTECH TECHNOLOGY LIMITED (GB) | 2000-10-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010009770-A1 | Process for the preparation of prostaglandin precursors | ADH1A, ADH1C, ADH5 | LMNA 2426/4885PKM 974/4885HSD17B10 106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.