Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GSR | P00390 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13578972 | 0.80 | LMNA (0.40) | LMNAALDH1A1CYP3A4GSRCPB2 | |
| SCHEMBL15617969 | 0.78 | LMNA (0.43) | LMNAALDH1A1CYP3A4GSRCPB2 | |
| SCHEMBL17613370 | 0.78 | LMNA (0.37) | LMNAALDH1A1CYP3A4GSRCPB2 | |
| SCHEMBL18538943 | 0.78 | LMNA (0.37) | LMNAALDH1A1CYP3A4GSRCPB2 | |
| SCHEMBL9713705 | 0.78 | ALDH1A1 (0.37) | ALDH1A1CYP3A4 | |
| SCHEMBL13041674 | 0.77 | CYP3A4 (0.44) | LMNAALDH1A1CYP3A4GSRCPB2 | |
| SCHEMBL183936 | 0.76 | LMNA (0.46) | LMNAALDH1A1GSRCPB2RNPEP | |
| SCHEMBL13897063 | 0.76 | TSHR (0.37) | — | |
| SCHEMBL12641739 | 0.76 | RNPEP (0.36) | LMNAALDH1A1CYP3A4GSRCPB2 | |
| SCHEMBL22995685 | 0.76 | MAPK1 (0.38) | LMNAALDH1A1CYP3A4GSRCPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10925970-B2 | Site selective conjugation of an oligonucleotide conjugate or a small molecule to a metal binding protein | AFFYCON APS (DK) | 2021-02-23 | — | — | US | disclosed |
| US-20170354743-A1 | SITE SELECTIVE CONJUGATION OF AN OLIGONUCLEOTIDE CONJUGATE OR A SMALL MOLECULE TO A METAL BINDING PROTEIN | AFFYCON APS (DK) | 2017-12-14 | — | — | US | disclosed |
| US-20170354743-A1 | SITE SELECTIVE CONJUGATION OF AN OLIGONUCLEOTIDE CONJUGATE OR A SMALL MOLECULE TO A METAL BINDING PROTEIN | AFFYCON APS (DK) | 2017-12-14 | — | — | US | disclosed |
| WO-2016005474-A1 | SITE SELECTIVE CONJUGATION OF AN OLIGONUCLEOTIDE CONJUGATE OR A SMALL MOLECULE TO A METAL BINDING PROTEIN | AFFYCON APS (DK) | 2016-01-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10925970-B2 | Site selective conjugation of an oligonucleotide conjugate or a small molecule to a metal binding protein | CD2BP2, CACYBP, CALCOCO2 | LMNA 3731/4885ALDH1A1 4588/4885CYP3A4 4803/4885 |
| US-20170354743-A1 | SITE SELECTIVE CONJUGATION OF AN OLIGONUCLEOTIDE CONJUGATE OR A SMALL MOLECULE TO A METAL BINDING PROTEIN | CD2BP2, CACYBP, CALCOCO2 | LMNA 3731/4885ALDH1A1 4588/4885CYP3A4 4803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.