Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GSR | P00390 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13578972 | 0.79 | LMNA (0.40) | LMNACPB2CYP3A4ALDH1A1GSR | |
| SCHEMBL18501604 | 0.77 | MAPK1 (0.34) | MAPK1LMNA | |
| SCHEMBL17471306 | 0.77 | MAPK1 (0.52) | MAPK1 | |
| SCHEMBL15617969 | 0.77 | LMNA (0.43) | LMNACPB2CYP3A4ALDH1A1GSR | |
| SCHEMBL17613370 | 0.76 | LMNA (0.37) | LMNACPB2CYP3A4ALDH1A1GSR | |
| SCHEMBL18538943 | 0.76 | LMNA (0.37) | LMNACPB2CYP3A4ALDH1A1GSR | |
| SCHEMBL17430657 | 0.76 | LMNA (0.38) | LMNACPB2CYP3A4ALDH1A1GSR | |
| SCHEMBL13041674 | 0.76 | CYP3A4 (0.44) | LMNACPB2CYP3A4ALDH1A1GSR | |
| SCHEMBL25552380 | 0.75 | CYP3A4 (0.31) | CPB2CYP3A4 | |
| SCHEMBL183936 | 0.75 | LMNA (0.46) | LMNACPB2ALDH1A1GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11634762-B2 | RT-qPCR molecular detection and diagnosis | CHEMGENES CORPORATION (US) | 2023-04-25 | — | — | US | disclosed |
| US-20220186222-A1 | LINKAGE MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2022-06-16 | — | — | US | disclosed |
| US-20210355551-A1 | RT-qPCR Molecular Detection and Diagnosis of 2019 Novel Coronavirus | CHEMGENES CORPORATION | 2021-11-18 | — | — | US | disclosed |
| US-20210355523-A1 | RT-qPCR Molecular Detection and Diagnosis | CHEMGENES CORPORATION | 2021-11-18 | — | — | US | disclosed |
| WO-2021030778-A1 | LINKAGE MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2021-02-18 | — | — | WO | disclosed |