Sugi Predict

Sugi Predict / Compounds / SCHEMBL1743355

SCHEMBL1743355

SCHEMBL1743355

[c]1coc2ccc3ccccc3c12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 4/20 0.42
▸ HSD17B10 Q99714 3/20 0.42
▸ ALDH1A1 P00352 3/20 0.42
▸ TSHR P16473 3/20 0.42
▸ CYP2A6 P11509 3/20 0.42
▸ HPRT1 P00492 1/20 0.39
▸ MCL1 Q07820 1/20 0.37
▸ HIF1A Q16665 1/20 0.37
▸ CYP1B1 Q16678 1/20 0.37
▸ POLB P06746 1/20 0.36
▸ PTPN1 P18031 1/20 0.36
▸ MAPT P10636 3/20 0.35
▸ KDM4E B2RXH2 2/20 0.35
▸ L3MBTL1 Q9Y468 2/20 0.35
▸ GLA P06280 1/20 0.35
▸ HPGD P15428 1/20 0.35
▸ HTT P42858 1/20 0.35
▸ HNF4A P41235 1/20 0.34
▸ CYP1A2 P05177 2/20 0.33
▸ PAX8 Q06710 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1743358 0.68 ALDH1A1 (0.42) TDP1HSD17B10ALDH1A1TSHRCYP2A6
SCHEMBL25021 0.66 ALDH1A1 (0.50) TDP1HSD17B10ALDH1A1TSHRCYP2A6
SCHEMBL30091394 0.64 TDP1 (0.55) TDP1HSD17B10ALDH1A1TSHRCYP2A6
SCHEMBL415466 0.64 TDP1 (0.55) TDP1HSD17B10ALDH1A1TSHRCYP2A6
SCHEMBL2519617 0.64 ALDH1A1 (0.48) TDP1HSD17B10ALDH1A1TSHRCYP2A6
SCHEMBL420462 0.64 ALDH1A1 (0.55) TDP1HSD17B10ALDH1A1TSHRCYP2A6
Phenanthrene SCHEMBL29477074 0.64 CYP2A6 (1.00) TDP1HSD17B10ALDH1A1TSHRCYP2A6
Phenanthrene SCHEMBL7643 0.64 CYP2A6 (1.00) TDP1HSD17B10ALDH1A1TSHRCYP2A6
Phenanthrene SCHEMBL29358486 0.64 CYP2A6 (1.00) TDP1HSD17B10ALDH1A1TSHRCYP2A6
Phenanthrene SCHEMBL30932938 0.64 CYP2A6 (1.00) TDP1HSD17B10ALDH1A1TSHRCYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4399199-A1 (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS Reuter Chemische Apparatebau e.K. (DE) 2024-07-17 — — EP claimed
EP-4399200-A1 (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS Mitsubishi Gas Chemical Company, Inc. (JP) 2024-07-17 — — EP claimed
WO-2023036868-A1 (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS REUTER CHEMISCHE APPARATEBAU E.K. (DE) 2023-03-16 — — WO claimed
WO-2023038156-A1 (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-03-16 — — WO claimed
CN-106575713-B Light-emitting device, electronic apparatus, and lighting device 株式会社半导体能源研究所 2019-01-25 — — CN claimed
CN-108101875-A Organic compound, light-emitting component, light-emitting device, electronic equipment and lighting device 株式会社半导体能源研究所 2018-06-01 — — CN claimed
CN-106575713-A Light-emitting device, electronic apparatus, and lighting device 株式会社半导体能源研究所 2017-04-19 — — CN claimed
CN-105683173-A Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device 株式会社半导体能源研究所 2016-06-15 — — CN claimed
EP-2388255-A1 Polysubstituted benzofurans and medicinal applications thereof Ikerchem, S.L. (ES) 2011-11-23 — — EP claimed
US-8038466-B1 Power receptacle with enlarged heat dissipation path formed on mating face and power connector assembly thereof ALLTOP ELECTRONICS (SUZHOU) CO., LTD (CN) 2011-10-18 — — US claimed
US-20040002487-A1 Protease inhibitors MARQUIS ROBERT WELLS (US) 2004-01-01 — — US claimed
US-20030225061-A1 Protease inhibitors MARQUIS ROBERT WELLS (US) 2003-12-04 — — US claimed
CN-1444481-A Protease inhibitors SMITHKLINE BEECHAM CORP (US) 2003-09-24 — — CN claimed
US-20030144175-A1 Protease inhibitors SMITHKLINE BEECHAM CORPORATION 2003-07-31 — — US claimed
WO-2003053331-A2 PROTEASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2003-07-03 — — WO claimed
EP-1307204-A1 PROTEASE INHIBITORS SmithKline Beecham Corporation (US) 2003-05-07 — — EP claimed
US-20020147188-A1 Protease inhibitors SMITHKLINE BEECHAM CORPORATION 2002-10-10 — — US claimed
WO-2001095911-A1 PROTEASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2001-12-20 — — WO claimed
EP-0670831-A1 QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1995-09-13 — — EP claimed
WO-1995009159-A1 QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1995-04-06 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030225061-A1 Protease inhibitors CTSK, MMP13, CTSZ TDP1 1653/4885HSD17B10 3057/4885ALDH1A1 3651/4885
US-20020147188-A1 Protease inhibitors CTSK, MMP13, CTSZ TDP1 1653/4885HSD17B10 3057/4885ALDH1A1 3651/4885
US-20040002487-A1 Protease inhibitors CTSK, MMP13, CTSZ TDP1 1653/4885HSD17B10 3057/4885ALDH1A1 3651/4885
US-20030144175-A1 Protease inhibitors CTSK, MMP13, CTSZ TDP1 1653/4885HSD17B10 3057/4885ALDH1A1 3651/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.