Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.51 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KRAS | P01116 | 12/20 | 0.45 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.45 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | HINT1 | P49773 | 1/20 | 0.43 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.43 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.43 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14659959 | 0.94 | NT5E (0.51) | NT5ETGM2POLBKRASFUT5 | |
| SCHEMBL309062 | 0.90 | TGM2 (0.53) | NT5ETGM2POLBKRASFUT5 | |
| SCHEMBL4076696 | 0.90 | POLG (0.53) | NT5ETGM2POLBKRASFUT5 | |
| SCHEMBL28252468 | 0.85 | HINT1 (0.44) | NT5ETGM2HINT1 | |
| Triphosphate SCHEMBL28238456 | 0.85 | PNP (0.49) | NT5ETGM2POLBKRASFUT5 | |
| SCHEMBL13626438 | 0.85 | ADORA3 (0.47) | NT5EHINT1 | |
| SCHEMBL18537401 | 0.85 | ADORA3 (0.47) | NT5EHINT1 | |
| SCHEMBL14620703 | 0.85 | ADORA3 (0.47) | NT5EHINT1 | |
| SCHEMBL116166 | 0.85 | ADORA3 (0.47) | NT5EHINT1 | |
| SCHEMBL16258667 | 0.85 | ADORA3 (0.47) | NT5EHINT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385951-A2 | PHOSPHORAMIDATE DERIVATIVES OF GUANOSINE NUCLEOSIDE COMPOUNDS FOR TREATMENT OF VIRAL INFECTIONS | University College Cardiff Consultants, Ltd. (GB) | 2011-11-16 | — | — | EP | disclosed |
| US-20110254856-A1 | MOBILE TERMINAL AND METHOD OF CONTROLLING OPERATION OF THE MOBILE TERMINAL | LG ELECTRONICS INC. (KR) | 2011-10-20 | — | — | US | disclosed |
| WO-2010081082-A2 | PHOSPHORAMIDATE DERIVATIVES OF GUANOSINE NUCLEOSIDE COMPOUNDS FOR TREATMENT OF VIRAL INFECTIONS | UNIVERSITY COLLEGE OF CARDIFF CONSULTANTS LIMITED (GB) | 2010-07-15 | — | — | WO | disclosed |