Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 7/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 7/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 7/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | AURKA | O14965 | 2/20 | 0.32 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | PRKCA | P17252 | 2/20 | 0.32 |
| ▸ | JAK1 | P23458 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17437529 | 0.95 | CYP11B2 (0.37) | ALDH1A1CYP11B1CYP11B2ALOX15RXFP1 | |
| SCHEMBL17437480 | 0.89 | KDM4E (0.34) | KDM4EALDH1A1MAPK1ADORA3ADORA2A | |
| SCHEMBL17437486 | 0.84 | SLC9A1 (0.33) | ALDH1A1CYP11B1CYP11B2ALOX15 | |
| SCHEMBL17437381 | 0.82 | CRHR1 (0.35) | ALDH1A1ADORA3ADORA2AADORA1MEN1 | |
| SCHEMBL17437313 | 0.81 | MAPT (0.34) | KDM4EALDH1A1MAPK1ADORA2AMEN1 | |
| SCHEMBL17437512 | 0.80 | CYP11B2 (0.34) | CYP11B2ADORA2A | |
| SCHEMBL17437327 | 0.80 | ADORA3 (0.39) | ADORA3ADORA2AADORA1AURKAJAK2 | |
| SCHEMBL17437460 | 0.78 | RPS6KA5 (0.34) | ADORA2A | |
| SCHEMBL17437316 | 0.78 | KDM4E (0.36) | KDM4EALDH1A1MAPK1CYP11B1CYP11B2 | |
| SCHEMBL17437394 | 0.77 | CYP1A2 (0.33) | CYP11B1CYP11B2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170050963-A1 | MICROBICIDALLY ACTIVE IMIDAZOPYRIDINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-02-23 | — | — | US | disclosed |
| US-9512120-B2 | Microbicidally active imidazopyridine derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2016-12-06 | — | — | US | disclosed |
| US-20160016949-A1 | MICROBICIDALLY ACTIVE IMIDAZOPYRIDINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170050963-A1 | MICROBICIDALLY ACTIVE IMIDAZOPYRIDINE DERIVATIVES | IDO1, IDO2, FOXM1 | KDM4E 1452/4885ALDH1A1 928/4885MAPK1 1737/4885 |
| US-20160016949-A1 | MICROBICIDALLY ACTIVE IMIDAZOPYRIDINE DERIVATIVES | IDO1, IDO2, FOXM1 | KDM4E 1452/4885ALDH1A1 928/4885MAPK1 1737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.