Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 1/20 | 0.38 |
| ▸ | METTL3 | Q86U44 | 5/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | AXL | P30530 | 2/20 | 0.34 |
| ▸ | WEE1 | P30291 | 1/20 | 0.34 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 3/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1742673 | 0.87 | BCHE (0.36) | — | |
| SCHEMBL476817 | 0.74 | STS (0.39) | JAK2 | |
| SCHEMBL17631624 | 0.74 | HDAC8 (0.39) | NR1H2 | |
| Tert-Butyl Formate SCHEMBL27831645 | 0.73 | IDO1 (0.46) | DHPSIDO1AXLNOS1TRPV1 | |
| SCHEMBL13583956 | 0.72 | GPR119 (0.36) | NR1H2 | |
| SCHEMBL277055 | 0.71 | NOS1 (0.59) | DHPSBRAFIDO1AXLNOS1 | |
| Hydrochloric Acid SCHEMBL6647093 | 0.70 | NOS1 (0.57) | DHPSBRAFIDO1AXLNOS1 | |
| SCHEMBL3673763 | 0.69 | TRPV1 (0.53) | TRPV1 | |
| SCHEMBL6891951 | 0.69 | MEN1 (0.43) | NR1H2 | |
| SCHEMBL476868 | 0.67 | USP30 (0.36) | JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2387560-A2 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | Abbott Laboratories (US) | 2011-11-23 | — | — | EP | disclosed |
| US-8042193-B1 | Systems and methods for controlling data access by use of a universal anonymous identifier | Albright Associates (US) | 2011-10-18 | — | — | US | disclosed |
| WO-2010083441-A2 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBOTT LABORATORIES (US) | 2010-07-22 | — | — | WO | disclosed |