SCHEMBL3673763

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25141629	0.86	PARP1 (0.48)	TRPV1CKS1BSKP1SKP2CHRM2
	SCHEMBL3969186	0.84	CYP11B2 (0.47)	CKS1BSKP1SKP2CHRM2CHRM4
	SCHEMBL17739091	0.84	TRPV1 (0.58)	TRPV1ALDH1A1MAPT
	SCHEMBL27804607	0.82	TRPV1 (0.58)	TRPV1MAPT
	SCHEMBL30485702	0.81	IDO1 (0.57)	CKS1BSKP1SKP2CHRM2CHRM4
	SCHEMBL20580826	0.81	IDO1 (0.46)	TRPV1CKS1BSKP1SKP2CHRM2
	SCHEMBL25366812	0.81	IDO1 (0.57)	CKS1BSKP1SKP2CHRM2CHRM4
	SCHEMBL5068821	0.81	KIT (0.51)	CKS1BSKP1SKP2CHRM2CHRM4
	SCHEMBL3721916	0.81	PIK3CD (0.56)	CKS1BSKP1SKP2KITMAPT
	SCHEMBL1537795	0.81	GAA (0.60)	MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.