SCHEMBL17439186

SCHEMBL17439186

CC(=O)CC(=O)ONC(C)=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 2/20 0.55
GAA P10253 2/20 0.55
SI P14410 2/20 0.55
MGAM2 Q2M2H8 2/20 0.55
KDM4E B2RXH2 3/20 0.33
TSHR P16473 3/20 0.33
HTT P42858 1/20 0.33
LMNA P02545 1/20 0.33
KDM6B O15054 1/20 0.32
KDM5C P41229 1/20 0.32
EGLN1 Q9GZT9 1/20 0.32
PHF8 Q9UPP1 1/20 0.32
KDM2A Q9Y2K7 1/20 0.32
CRBN Q96SW2 1/20 0.32
ALDH1A1 P00352 3/20 0.32
TDP1 Q9NUW8 1/20 0.32
CA2 P00918 1/20 0.32
PTGS1 P23219 1/20 0.32
MMP12 P39900 1/20 0.32
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7263173 0.89 MGAM (0.39) MGAMGAASIMGAM2KDM4E
SCHEMBL19638975 0.84
SCHEMBL5961642 0.82 MGAM (0.52) MGAMGAASIMGAM2KDM4E
SCHEMBL7263177 0.82 LDHA (0.38) MGAMGAASIMGAM2KDM4E
SCHEMBL5037696 0.79
SCHEMBL27901765 0.78 MGAM (0.48) MGAMGAASIMGAM2KDM4E
SCHEMBL2353352 0.77
SCHEMBL28286077 0.77 TSHR (0.52) MGAMGAASIMGAM2KDM4E
SCHEMBL562095 0.77 MGAM (0.46) MGAMGAASIMGAM2ALDH1A1
SCHEMBL7276621 0.77 GAA (0.65) MGAMGAASIMGAM2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119143651-A Method for preparing pyrrole and furan compounds from N-acetylglucosamine 南京工业大学 2024-12-17 CN disclosed
US-9862978-B2 Method for preparing (2RS)-amino-(3S)-hydroxy-butyric acid and its derivatives AMINOLOGICS CO. LTD. (KR) 2018-01-09 US disclosed
US-20160017389-A1 METHOD FOR PREPARING (2RS)-AMINO-(3S)-HYDROXY-BUTYRIC ACID AND ITS DERIVATIVES AMINOLOGICS CO., LTD. (KR) 2016-01-21 US disclosed
CN-1021789-C Compositions containing 1, 2, 4-triazole derivatives, method for preparing same and use thereof as plant protection agents HOECHST AG (DE) 1993-08-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160017389-A1 METHOD FOR PREPARING (2RS)-AMINO-(3S)-HYDROXY-BUTYRIC ACID AND ITS DERIVATIVES ALAD, CYP51A1, ALDH7A1 MGAM 569/4885GAA 790/4885SI 34/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.