Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SI | P14410 | 2/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17439186 | 0.89 | MGAM (0.55) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL7263177 | 0.87 | LDHA (0.38) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL7276621 | 0.86 | GAA (0.65) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL28830034 | 0.84 | DGAT1 (0.34) | GAACA2TDP1LMNA | |
| SCHEMBL19638975 | 0.83 | — | — | |
| SCHEMBL5037696 | 0.83 | — | — | |
| SCHEMBL2353352 | 0.81 | — | — | |
| SCHEMBL28286077 | 0.81 | TSHR (0.52) | MGAMGAASIMGAM2TSHR | |
| Butane SCHEMBL1060217 | 0.81 | FFAR3 (0.33) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL9839492 | 0.79 | ALDH1A1 (0.50) | MGAMGAASIMGAM2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1688298-A | Composition, Synthesis and Therapeutic Use of Polyamines | MURPHY MICHAEL A (US) | 2005-10-26 | — | — | CN | disclosed |
| WO-2003016248-A2 | BICYCLIC HYDROXAMATES AS INHIBITORS OF MATRIX METALLOPROTEINASES AND/OR TNF-$G(A) CONVERTING ENZYME (TACE) | BRISTOL-MYERS SQUIBB COMPANY PATENT DEPARTMENT (US) | 2003-02-27 | — | — | WO | disclosed |
| CN-1343219-A | Substituted phenethylamine derivatives | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2002-04-03 | — | — | CN | disclosed |
| CN-1021789-C | Compositions containing 1, 2, 4-triazole derivatives, method for preparing same and use thereof as plant protection agents | HOECHST AG (DE) | 1993-08-18 | — | — | CN | disclosed |