Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL17439397

C=CCN(CC=C)C1CCCCC1.N

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.40
ADH1A P07327 8/20 0.34
ADH1C P00326 5/20 0.34
SIGMAR1 Q99720 1/20 0.32
CYP2D6 P10635 2/20 0.32
CYP2C9 P11712 2/20 0.32
HSD17B10 Q99714 1/20 0.32
TSHR P16473 1/20 0.32
ADH4 P08319 1/20 0.31
ADH1B P00325 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30750 0.98 ALDH1A1 (0.41) ALDH1A1ADH1AADH1CSIGMAR1CYP2D6
Hydrochloric Acid SCHEMBL2957420 0.95 ALDH1A1 (0.40) ALDH1A1ADH1AADH1CSIGMAR1CYP2D6
Fluoride SCHEMBL9620616 0.95 ALDH1A1 (0.40) ALDH1A1ADH1AADH1CSIGMAR1CYP2D6
SCHEMBL2163192 0.95 ALDH1A1 (0.38) ALDH1A1ADH1AADH1CSIGMAR1ADH4
SCHEMBL10582372 0.88 ALDH1A1 (0.39) ALDH1A1ADH1AADH1CCYP2D6CYP2C9
SCHEMBL2363531 0.85 SIGMAR1 (0.35) SIGMAR1
SCHEMBL10975387 0.85 ALDH1A1 (0.37) ALDH1A1ADH1AADH1C
SCHEMBL3467156 0.85 ADH1A (0.44) ALDH1A1ADH1AADH1CSIGMAR1ADH1B
SCHEMBL3429552 0.81 ADH1A (0.47) ALDH1A1ADH1AADH1C
SCHEMBL10716961 0.81 ALDH1A1 (0.42) ALDH1A1ADH1ACYP2D6CYP2C9HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10035874-B2 Epoxide-based composition EVONIK DEGUSSA GMBH (DE) 2018-07-31 US disclosed
EP-3169715-B1 EPOXIDE-BASED COMPOSITION EVONIK DEGUSSA GMBH (DE) 2018-04-25 EP disclosed
EP-3169715-A1 EPOXIDE-BASED COMPOSITION Air Products and Chemicals, Inc. (US) 2017-05-24 EP disclosed
US-20160017087-A1 Epoxide-Based Composition AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-01-21 US disclosed
WO-2016010953-A1 EPOXIDE-BASED COMPOSITION AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-01-21 WO disclosed