SCHEMBL2363531

SCHEMBL2363531

C=CCN(CC=C)C1CCC(N(CC=C)CC=C)CC1

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.35
LSS P48449 1/20 0.33
OPRM1 P35372 1/20 0.31
OPRD1 P41143 1/20 0.31
OPRK1 P41145 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2163192 0.89 ALDH1A1 (0.38) SIGMAR1
SCHEMBL7323478 0.88 LSS (0.32) SIGMAR1LSSOPRM1OPRD1OPRK1
SCHEMBL30750 0.87 ALDH1A1 (0.41) SIGMAR1
Fluoride SCHEMBL9620616 0.85 ALDH1A1 (0.40) SIGMAR1
Ammonia Solution, Strong SCHEMBL17439397 0.85 ALDH1A1 (0.40) SIGMAR1
Hydrochloric Acid SCHEMBL2957420 0.85 ALDH1A1 (0.40) SIGMAR1
SCHEMBL3798088 0.83 SLC6A2 (0.34) SIGMAR1
SCHEMBL7269723 0.83 SIGMAR1 (0.31) SIGMAR1
SCHEMBL1044449 0.79 SIGMAR1 (0.33) SIGMAR1LSSOPRM1OPRD1OPRK1
SCHEMBL24693688 0.79 OPRM1 (0.32) OPRM1OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977432-B2 Comprising at least two polymer end blocks and at least one saturated polymer interior block wherein each end block is resistant to lithiation and at least one interior block is susceptible to lithiation; for semi-permeable membrane with high water transport properties that maintains wet strength KRATON POLYMERS U.S. LLC (US) 2011-07-12 US disclosed
US-20080171828-A1 FUNCTIONALIZED BLOCK COPOLYMERS, METHOD FOR MAKING SAME, AND VARIOUS USES FOR SUCH BLOCK COPOLYMERS KRATON POLYMERS U.S. LLC. (US) 2008-07-17 US disclosed
US-H1485-H Hydrogenated block copolymers grafted on carboxy polymers SHELL OIL CO. (US) 1995-09-05 US disclosed
US-H1438-H With carbon dioxide, heat stable SHELL OIL COMPANY (US) 1995-05-02 US disclosed
US-H1405-H Emulsifying and blending with block copolymer of hydrogenated conjugated diene and carboxylated monoalkenyl aromatic hydrocarbon SHELL OIL COMPANY (US) 1995-01-03 US disclosed
EP-0565206-A2 Epoxy resin composition SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1993-10-13 EP disclosed
EP-0329254-B1 LUBRICANT COMPOSITION CONTAINING A VISCOSITY INDEX IMPROVER HAVING DISPERSANT PROPERTIES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-06-24 EP disclosed
EP-0487191-A2 Impact modified polyphenylene sulfide HOECHST CELANESE CORPORATION (US) 1992-05-27 EP disclosed
US-5070127-A ENGINEERING THERMOPLASTICS, BLENDS, BLOCK POLYMERS, GRAFT POLY MERS HOECHST CELANESE CORPORATION (US) 1991-12-03 US disclosed
US-5047465-A Impact modified polyphenylene sulfide HOECHST CELANESE CORPORATION (US) 1991-09-10 US disclosed
US-4868245-A MECHANICAL PROPERTIES SHELL OIL COMPANY (US) 1989-09-19 US disclosed
EP-0329254-A1 Lubricant composition containing a viscosity index improver having dispersant properties SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-08-23 EP disclosed
US-4797447-A MODIFIED BUTADIENE-STYRENE COPOLYMERS SHELL OIL COMPANY (US) 1989-01-10 US disclosed
US-4783503-A GRAFT POLYMERS SHELL OIL COMPANY (US) 1988-11-08 US disclosed
US-4402843-A Viscosity index improvers with dispersant properties prepared by reaction of lithiated hydrogenated copolymers with 4-substituted aminopyridines PHILLIPS PETROLEUM COMPANY (US) 1983-09-06 US disclosed
US-4402844-A Viscosity index improvers with dispersant properties prepared by reaction of lithiated hydrogenated copolymers with substituted aminolactams PHILLIPS PETROLEUM COMPANY (US) 1983-09-06 US disclosed
EP-0024734-A2 Nitrogen-containing organic compound grafted copolymer, hydrocarbon fuel compositions, additive concentrate, and use of said copolymer in fuels PHILLIPS PETROLEUM COMPANY (US) 1981-03-11 EP disclosed
US-4238202-A NITROGEN-CONTAINING ORGANIC COMPOUND-GRAFTED, HYDROGENATED CONJUGATED DIENE-MONOVINYLARENE COPOLYMER PHILLIPS PETROLEUM COMPANY (US) 1980-12-09 US disclosed
EP-0001547-A1 Process for preparing organo-nitrogen grafted copolymers, the copolymers so produced and mineral oil compositions containing them PHILLIPS PETROLEUM COMPANY (US) 1979-05-02 EP disclosed
US-4145298-A HYDROGENATED LITHIATED COPOLYMERS GRAFTED WITH ORGANIC NITROGEN COMPOUNDS AS VISCOSITY INDEX IMPROVERS HAVING DISPERSANT PROPERTIES PHILLIPS PETROLEUM COMPANY (US) 1979-03-20 US disclosed