Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27792580 | 0.85 | KMT2A (0.47) | KMT2AMAPTLMNACYP1A2CYP2C9 | |
| SCHEMBL9196209 | 0.85 | KMT2A (0.47) | KMT2AMAPTLMNACYP1A2CYP2C9 | |
| SCHEMBL3654232 | 0.80 | S1PR2 (0.41) | KMT2AMAPTLMNACYP1A2CYP2C9 | |
| SCHEMBL9196580 | 0.76 | ALDH1A1 (0.50) | KMT2AMAPTLMNACYP1A2CYP2C9 | |
| SCHEMBL30318701 | 0.75 | PDE2A (0.52) | KMT2AMAPTLMNACYP1A2ALDH1A1 | |
| SCHEMBL10241852 | 0.75 | PDE2A (0.52) | KMT2AMAPTLMNACYP1A2ALDH1A1 | |
| SCHEMBL11344361 | 0.75 | LMNA (0.49) | KMT2AMAPTLMNAS1PR2ALDH1A1 | |
| SCHEMBL8389479 | 0.73 | S1PR2 (0.35) | MAPTS1PR2ALDH1A1 | |
| SCHEMBL2928544 | 0.73 | S1PR2 (0.45) | KMT2AMAPTLMNAS1PR2ALDH1A1 | |
| SCHEMBL985142 | 0.72 | KMO (0.39) | KMT2AMAPTLMNACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2386558-B1 | CGRP antagonists | BOEHRINGER INGELHEIM INT (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2205590-B1 | CGRP ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2014-06-04 | — | — | EP | disclosed |
| EP-2205599-B1 | CGRP ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2012-06-06 | — | — | EP | disclosed |
| EP-2386558-A1 | CGRP antagonists | Boehringer Ingelheim International GmbH (DE) | 2011-11-16 | — | — | EP | disclosed |
| US-20110253722-A1 | METHOD AND SYSTEM FOR WATERPROOFING A MOBILE DEVICE | TOMORROW'S INNOVATIONS (US) | 2011-10-20 | — | — | US | disclosed |
| EP-0497851-B1 | SULPHONATED HETEROCYCLIC CARBOXAMIDES AS HERBICIDES, GROWTH REGULATORS OR FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1995-01-04 | — | — | EP | disclosed |
| EP-0497851-A1 | SULPHONATED HETEROCYCLIC CARBOXAMIDES AS HERBICIDES, GROWTH REGULATORS OR FUNGICIDES. | HOECHST AG (DE) | 1992-08-12 | — | — | EP | disclosed |
| WO-1991006541-A1 | SULPHONATED HETEROCYCLIC CARBOXAMIDES AS HERBICIDES, GROWTH REGULATORS OR FUNGICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-05-16 | — | — | WO | disclosed |