Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.54 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.53 |
| ▸ | ACACB | O00763 | 3/20 | 0.51 |
| ▸ | ACACA | Q13085 | 3/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL167640 | 0.85 | RAB9A (0.83) | MAPTHPGDRAB9ASRD5A2PARP10 | |
| SCHEMBL1744599 | 0.85 | LTA4H (0.52) | SRD5A2ACACBACACAPTGS1 | |
| SCHEMBL506349 | 0.85 | LTA4H (0.52) | SRD5A2ACACBACACAPTGS1 | |
| SCHEMBL7598855 | 0.85 | LTA4H (0.52) | SRD5A2ACACBACACAPTGS1 | |
| Hydrochloric Acid SCHEMBL14831299 | 0.83 | LTA4H (0.50) | RAB9ASRD5A2ACACBACACAPTGS1 | |
| Hydrochloric Acid SCHEMBL22159302 | 0.83 | LTA4H (0.50) | RAB9ASRD5A2ACACBACACAPTGS1 | |
| Hydrochloric Acid SCHEMBL11741463 | 0.83 | LTA4H (0.50) | RAB9ASRD5A2ACACBACACAPTGS1 | |
| SCHEMBL4797264 | 0.83 | ROCK2 (0.50) | MAPTHPGDRAB9AALDH1A1SMN1; SMN2 | |
| Acetophenone SCHEMBL19028023 | 0.81 | MAPT (0.50) | MAPTHPGDPTGS1ALDH1A1SMN1; SMN2 | |
| SCHEMBL21935080 | 0.80 | MAPT (0.73) | MAPTHPGDRAB9ASRD5A2PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385983-A2 | TRANSAMINASE POLYPEPTIDES | Codexis, Inc. (US) | 2011-11-16 | — | — | EP | disclosed |
| US-D646886-S1 | Tip of an umbrella | Pro Performance Sports, L.L.C. (US) | 2011-10-18 | — | — | US | disclosed |