Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | NOS3 | P29474 | 2/20 | 0.47 |
| ▸ | NOS1 | P29475 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GRM8 | O00222 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetophenone SCHEMBL19028023 | 0.85 | MAPT (0.50) | MAPTHPGDLMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL22014063 | 0.84 | NOS3 (0.48) | NOS3NOS1MAPTHPGDLMNA | |
| SCHEMBL28953743 | 0.84 | ROCK2 (0.51) | ROCK2ROCK1ADRB2MAPTHPGD | |
| SCHEMBL1744124 | 0.83 | MAPT (0.59) | MAPTHPGDRAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL3783150 | 0.82 | PARP10 (0.53) | ROCK2ROCK1ADRB2NOS1MAPT | |
| SCHEMBL2129856 | 0.82 | ANPEP (0.57) | ROCK2ROCK1ADRB2HPGDKMT2A | |
| SCHEMBL8254658 | 0.82 | PARP10 (0.53) | ROCK2ROCK1ADRB2NOS1MAPT | |
| SCHEMBL4448319 | 0.82 | ANPEP (0.57) | ROCK2ROCK1ADRB2HPGDKMT2A | |
| SCHEMBL12052082 | 0.82 | PARP10 (0.53) | ROCK2ROCK1ADRB2NOS1MAPT | |
| SCHEMBL4878931 | 0.82 | ANPEP (0.57) | ROCK2ROCK1ADRB2HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7321055-B2 | Production method of optically active dephenylalanine compounds | AJINOMOTO CO., INC. (JP) | 2008-01-22 | — | — | US | claimed |
| US-20070032658-A1 | Production method of optically active dephenylalanine compounds | AJINOMOTO CO., INC. (JP) | 2007-02-08 | — | — | US | claimed |
| EP-1749816-A1 | Production method of optically active diphenylalanine compounds | Ajinomoto Co., Ltd. (JP) | 2007-02-07 | — | — | EP | claimed |
| US-20170291885-A1 | METHOD FOR PREPARING ENAMIDE COMPOUND AND RUTHENIUM COMPLEX CATALYST USED THEREIN | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2017-10-12 | — | — | US | disclosed |
| US-7321055-B2 | Production method of optically active dephenylalanine compounds | AJINOMOTO CO., INC. (JP) | 2008-01-22 | — | — | US | disclosed |
| US-20070032658-A1 | Production method of optically active dephenylalanine compounds | AJINOMOTO CO., INC. (JP) | 2007-02-08 | — | — | US | disclosed |
| EP-1749816-A1 | Production method of optically active diphenylalanine compounds | Ajinomoto Co., Ltd. (JP) | 2007-02-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032658-A1 | Production method of optically active dephenylalanine compounds | TYR, PAH, DDC | ROCK2 2004/4885ROCK1 1306/4885ADRB2 1338/4885 |
| US-20170291885-A1 | METHOD FOR PREPARING ENAMIDE COMPOUND AND RUTHENIUM COMPLEX CATALYST USED THEREIN | ENY2, ENO1, IDH1 | ROCK2 2210/4885ROCK1 3602/4885ADRB2 1146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.