Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 4/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.40 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | PPARG | P37231 | 4/20 | 0.30 |
| ▸ | PPARD | Q03181 | 4/20 | 0.30 |
| ▸ | PPARA | Q07869 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1805494 | 0.77 | HIF1A (0.39) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| SCHEMBL3335899 | 0.73 | — | — | |
| SCHEMBL10978667 | 0.73 | — | — | |
| SCHEMBL4785776 | 0.70 | HDAC3 (0.42) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| SCHEMBL23958618 | 0.65 | — | — | |
| SCHEMBL17620521 | 0.65 | — | — | |
| SCHEMBL11114847 | 0.65 | FFAR3 (0.37) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| Butyric Acid SCHEMBL1615529 | 0.64 | — | — | |
| SCHEMBL17621147 | 0.64 | — | — | |
| Butyric Acid SCHEMBL2052085 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11330821-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2022-05-17 | — | — | US | disclosed |
| EP-3288934-B1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-09-04 | — | — | EP | disclosed |
| EP-3169668-B1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-09-04 | — | — | EP | disclosed |
| US-20180116219-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-05-03 | — | — | US | disclosed |
| US-9944608-B2 | Herbicidal pyridazinone derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-17 | — | — | US | disclosed |
| EP-3288934-A1 | HERBICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2018-03-07 | — | — | EP | disclosed |
| US-20170166535-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-06-15 | — | — | US | disclosed |
| EP-3169668-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | Syngenta Participations AG (CH) | 2017-05-24 | — | — | EP | disclosed |
| WO-2016174072-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-11-03 | — | — | WO | disclosed |
| WO-2016008816-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11330821-B2 | Herbicidal compounds | DDT, HPD, HDHD5 | HDAC3 572/4885HDAC1 1041/4885HDAC2 667/4885 |
| US-20180116219-A1 | HERBICIDAL COMPOUNDS | DDT, HPD, HDHD5 | HDAC3 572/4885HDAC1 1041/4885HDAC2 667/4885 |
| US-20170166535-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | HPD, DDT, PDXK | HDAC3 786/4885HDAC1 900/4885HDAC2 1036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.