Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 3/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19136142 | 0.90 | METAP1 (0.51) | METAP1NPC1RAB9ASMN1; SMN2NR1I3 | |
| SCHEMBL25679160 | 0.84 | METAP1 (0.49) | METAP1NPC1RAB9ASMN1; SMN2AURKA | |
| SCHEMBL16404333 | 0.83 | METAP1 (0.61) | METAP1LMNAMAPTNPC1RAB9A | |
| SCHEMBL21667538 | 0.83 | MEN1 (0.54) | LMNAMAPTNPC1RAB9ARECQL | |
| SCHEMBL19169797 | 0.81 | PDE10A (0.56) | LMNAMAPTNPC1RAB9ARECQL | |
| SCHEMBL22186525 | 0.81 | ALDH1A1 (0.56) | LMNAMAPTNPC1RAB9ARECQL | |
| SCHEMBL11829152 | 0.81 | METAP1 (0.51) | METAP1MAPTNPC1RAB9ANR1I3 | |
| SCHEMBL13851830 | 0.80 | CYP1B1 (0.47) | LMNAMAPTNPC1RAB9ARECQL | |
| SCHEMBL24473221 | 0.80 | MEN1 (0.59) | LMNAMAPTNPC1RAB9ARECQL | |
| SCHEMBL17275213 | 0.80 | METAP1 (0.57) | METAP1LMNANPC1RAB9ACYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11201296-B2 | Compounds having fluorene structures | MERCK PATENT GMBH (DE) | 2021-12-14 | — | — | US | disclosed |
| EP-3328850-B1 | COMPOUNDS HAVING FLUORENE STRUCTURES | MERCK PATENT GMBH (DE) | 2020-11-11 | — | — | EP | disclosed |
| US-20180226587-A1 | COMPOUNDS HAVING FLUORENE STRUCTURES | MERCK PATENT GMBH (DE) | 2018-08-09 | — | — | US | disclosed |
| US-20180226587-A1 | COMPOUNDS HAVING FLUORENE STRUCTURES | MERCK PATENT GMBH (DE) | 2018-08-09 | — | — | US | disclosed |
| US-9780314-B2 | Compound for organic electric element, organic electric element comprising the same and electronic device thereof | DUK SAN NEOLUX CO., LTD. (KR) | 2017-10-03 | — | — | US | disclosed |
| US-9780314-B2 | Compound for organic electric element, organic electric element comprising the same and electronic device thereof | DUK SAN NEOLUX CO., LTD. (KR) | 2017-10-03 | — | — | US | disclosed |
| WO-2017016667-A1 | COMPOUNDS HAVING FLUORENE STRUCTURES | MERCK PATENT GMBH (DE) | 2017-02-02 | — | — | WO | disclosed |
| US-20160020408-A1 | COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF | DUK SAN NEOLUX CO., LTD. (KR) | 2016-01-21 | — | — | US | disclosed |
| US-20160020408-A1 | COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF | DUK SAN NEOLUX CO., LTD. (KR) | 2016-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180226587-A1 | COMPOUNDS HAVING FLUORENE STRUCTURES | FSCN1, EFNA1, FLNA | METAP1 3452/4885LMNA 2066/4885MAPT 489/4885 |
| US-20160020408-A1 | COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF | OR51E2, NFE2L2, ORAI2 | METAP1 3160/4885LMNA 2617/4885MAPT 1456/4885 |
| US-11201296-B2 | Compounds having fluorene structures | FSCN1, EFNA1, FLNA | METAP1 3452/4885LMNA 2066/4885MAPT 489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.