Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 12/20 | 0.51 |
| ▸ | S100A4 | P26447 | 4/20 | 0.51 |
| ▸ | MAP2K7 | O14733 | 2/20 | 0.47 |
| ▸ | CDC25A | P30304 | 2/20 | 0.47 |
| ▸ | CDC25B | P30305 | 2/20 | 0.47 |
| ▸ | P4HB | P07237 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4629512 | 0.80 | S100A4 (0.76) | SOAT1S100A4MAP2K7CDC25ACDC25B | |
| SCHEMBL4848419 | 0.79 | SOAT1 (0.78) | SOAT1S100A4MAP2K7CDC25ACDC25B | |
| SCHEMBL17445488 | 0.76 | CDC25B (0.78) | SOAT1S100A4MAP2K7CDC25ACDC25B | |
| SCHEMBL4657692 | 0.71 | CDC25B (0.56) | SOAT1S100A4MAP2K7CDC25ACDC25B | |
| SCHEMBL11842736 | 0.71 | ALDH1A1 (0.56) | ALDH1A1KDM4ECYP3A4MAPK1 | |
| SCHEMBL4784115 | 0.69 | PTPRC (0.50) | SOAT1S100A4MAP2K7CDC25ACDC25B | |
| SCHEMBL2599427 | 0.68 | SOAT1 (1.00) | SOAT1S100A4MAP2K7CDC25ACDC25B | |
| SCHEMBL9267240 | 0.68 | S100A4 (0.69) | SOAT1S100A4MAP2K7CDC25ACDC25B | |
| SCHEMBL18921828 | 0.68 | CYP1A2 (0.58) | ALDH1A1KDM4ECYP3A4MAPTMAPK1 | |
| SCHEMBL18921847 | 0.68 | CYP1A2 (0.58) | ALDH1A1KDM4ECYP3A4MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160017399-A1 | ELECTROCHEMICAL-BASED ANALYTICAL TEST STRIP WITH ENZYMATIC REAGENT LAYER CONTAINING A NAPHTHOQUINONE-BASED MEDIATOR AND FAD-GDH | LIFESCAN SCOTLAND LIMITED (GB) | 2016-01-21 | — | — | US | disclosed |
| US-20160017399-A1 | ELECTROCHEMICAL-BASED ANALYTICAL TEST STRIP WITH ENZYMATIC REAGENT LAYER CONTAINING A NAPHTHOQUINONE-BASED MEDIATOR AND FAD-GDH | LIFESCAN SCOTLAND LIMITED (GB) | 2016-01-21 | — | — | US | disclosed |