Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | LYN | P07948 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | TYMP | P19971 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17448661 | 0.84 | PGR (0.58) | ALDH1A1KDM4EMAPTHPGDKMT2A | |
| SCHEMBL17446075 | 0.82 | ALDH1A1 (0.65) | MAPK14ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL17446137 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KDM4EMAPTHPGDKMT2A | |
| SCHEMBL12066464 | 0.81 | ALDH1A1 (0.47) | MAPK14ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL4500559 | 0.73 | ALDH1A1 (0.48) | ALDH1A1KDM4EMAPTHPGDKMT2A | |
| SCHEMBL17446140 | 0.71 | ALDH1A1 (0.54) | ALDH1A1KDM4EMAPTHPGDKMT2A | |
| SCHEMBL11664568 | 0.71 | GRIK1 (0.50) | ALDH1A1MAPTKMT2ATP53BACE1 | |
| SCHEMBL10429722 | 0.70 | L3MBTL1 (0.48) | MAPK14ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL17446072 | 0.69 | ALDH1A1 (0.51) | ALDH1A1KDM4EMAPTHPGDKMT2A | |
| SCHEMBL8876920 | 0.68 | SLC9A1 (0.53) | ALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016010609-A1 | PREVENTION AND TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE | OHIO UNIVERSITY (US) | 2016-01-21 | — | — | WO | disclosed |