Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 14/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 5/20 | 0.37 |
| ▸ | CTSK | P43235 | 5/20 | 0.37 |
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19169463 | 0.83 | CTSL (0.40) | CTSLCTSSCTSKCTSB | |
| SCHEMBL17447542 | 0.83 | CTSS (0.41) | CTSLCCR2CTSSCTSKCTSB | |
| SCHEMBL17447512 | 0.80 | CTSL (0.39) | CTSLCTSSCTSKCTSB | |
| SCHEMBL22826896 | 0.79 | CTSL (0.42) | CTSLCTSSCTSKCTSB | |
| SCHEMBL15906757 | 0.75 | CTSL (0.42) | CTSLCTSSCTSKCTSB | |
| SCHEMBL18910044 | 0.74 | CTSL (0.44) | CTSLCTSSCTSKCTSB | |
| SCHEMBL17447513 | 0.72 | CTSS (0.40) | CTSLCCR2CTSSCTSKCTSB | |
| SCHEMBL19116799 | 0.70 | CTSL (0.46) | CTSLCTSSCTSKCTSB | |
| SCHEMBL13126736 | 0.69 | CCR2 (0.47) | CCR2 | |
| SCHEMBL27440700 | 0.69 | CTSL (0.37) | CTSLCTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016008582-A1 | SUBSTITUTED AZASPIRO(4.5)DECANE DERIVATIVES | Grünenthal GmbH (DE) | 2016-01-21 | — | — | WO | disclosed |