Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 15/20 | 0.44 |
| ▸ | CTSS | P25774 | 7/20 | 0.40 |
| ▸ | CTSK | P43235 | 7/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19116799 | 0.82 | CTSL (0.46) | CTSLCTSSCTSKCTSB | |
| SCHEMBL5673421 | 0.80 | CTSS (0.40) | CTSLCTSSCTSKCTSB | |
| SCHEMBL15427227 | 0.76 | CTSS (0.42) | CTSLCTSSCTSKCTSB | |
| SCHEMBL11972690 | 0.75 | EPHX2 (0.51) | — | |
| SCHEMBL17447482 | 0.74 | CTSL (0.46) | CTSLCTSSCTSKCTSB | |
| SCHEMBL13401138 | 0.72 | CTSL (0.49) | CTSLCTSSCTSKCTSB | |
| SCHEMBL15427226 | 0.72 | CTSS (0.42) | CTSLCTSSCTSKCTSB | |
| SCHEMBL2155600 | 0.71 | CTSL (0.46) | CTSLCTSSCTSKCTSB | |
| SCHEMBL3372481 | 0.71 | ALDH1A1 (0.41) | — | |
| SCHEMBL7571642 | 0.71 | CTSL (0.43) | CTSLCTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114981251-B | Dibenzofuran derivative cathepsin K inhibitor and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-114981251-A | Diphenyl furan derivative cathepsin K inhibitor and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-08-30 | — | — | CN | disclosed |
| WO-2017089389-A1 | TRYPANOSOMES INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2017-06-01 | — | — | WO | disclosed |