Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1744241 | 0.94 | DUT (0.40) | DUTSMN1; SMN2LMNAALDH1A1PKM | |
| SCHEMBL1744651 | 0.89 | DUT (0.41) | DUTDGAT1HTR7 | |
| SCHEMBL1746128 | 0.82 | GLS (0.34) | GAAALDH1A1CYP3A4TSHRRECQL | |
| SCHEMBL4511606 | 0.77 | HTR7 (0.51) | DUTHTR7 | |
| SCHEMBL1464500 | 0.75 | GLS (0.38) | DUTSMN1; SMN2LMNAGAAALDH1A1 | |
| SCHEMBL3997142 | 0.73 | PRKCI (0.45) | DUTDGAT1HTR7 | |
| SCHEMBL4001230 | 0.73 | DUT (0.45) | DUTDGAT1HTR7 | |
| SCHEMBL31487744 | 0.73 | DUT (0.41) | DUTLMNAALDH1A1DGAT1 | |
| SCHEMBL9091990 | 0.71 | HTR2A (0.48) | DUTCYP3A4HTR7 | |
| SCHEMBL30814634 | 0.71 | DUT (0.47) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385939-A1 | DIHYDROPYRIDONE AMIDES AS P2X7 MODULATORS | F. Hoffmann-La Roche AG (CH) | 2011-11-16 | — | — | EP | disclosed |
| US-8041551-B1 | Algorithm and architecture for multi-argument associative operations that minimizes the number of components using a latency of the components | THE MATHWORKS, INC. (US) | 2011-10-18 | — | — | US | disclosed |
| WO-2010072597-A1 | DIHYDROPYRIDONE AMIDES AS P2X7 MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-07-01 | — | — | WO | disclosed |