Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23014824 | 0.86 | HSD17B10 (0.41) | RAB9ASMN1; SMN2KDM4ETHRBTDP1 | |
| SCHEMBL1338721 | 0.83 | KCNH2 (0.41) | KCNH2RAB9ASMN1; SMN2KDM4ETHRB | |
| SCHEMBL13344429 | 0.81 | CYP2A6 (0.55) | KCNH2RAB9ACYP2A6 | |
| SCHEMBL3016789 | 0.80 | HDAC8 (0.35) | KCNH2HDAC8RAB9ATDP1CYP2A6 | |
| SCHEMBL517636 | 0.80 | NR3C1 (0.40) | ACACBHDAC8FFAR1TDP1 | |
| SCHEMBL11978605 | 0.78 | HRH3 (0.41) | — | |
| SCHEMBL670610 | 0.77 | LPL (0.45) | ACACBHDAC8THRBCYP2A6 | |
| SCHEMBL12037019 | 0.77 | TAAR1 (0.50) | KCNH2RAB9ASMN1; SMN2KDM4ETHRB | |
| SCHEMBL12344398 | 0.77 | L3MBTL1 (0.46) | ACACBKDM4E | |
| SCHEMBL11101026 | 0.77 | TSHR (0.58) | KCNH2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975022-B1 | NOVEL HYDROXAMIC ACID DERIVATIVE OR SALT THEREOF | FUJIFILM TOYAMA CHEMICAL CO LTD (JP) | 2019-05-08 | — | — | EP | disclosed |
| EP-2975022-A1 | NOVEL HYDROXAMIC ACID DERIVATIVE OR SALT THEREOF | Toyama Chemical Co., Ltd. (JP) | 2016-01-20 | — | — | EP | disclosed |