SCHEMBL1745281

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1745372	0.88	FFAR1 (0.58)	FFAR1FFAR4AKR1B1
	SCHEMBL9105728	0.83	NPC1 (0.53)	PTPN1NPC1RAB9A
	SCHEMBL1746499	0.79	RAB9A (0.55)	RAB9AVDRFFAR1FFAR4AKR1B1
	SCHEMBL1745247	0.76	FFAR1 (0.72)	NPC1RAB9AFFAR1FFAR4AKR1B1
	SCHEMBL1747136	0.76	FFAR1 (0.72)	NPC1RAB9AFFAR1FFAR4AKR1B1
	SCHEMBL2822600	0.76	FFAR1 (0.48)	VDRPPARDFFAR1FFAR4AKR1B1
	SCHEMBL2824806	0.76	FFAR1 (0.46)	VDRPPARDFFAR1FFAR4AKR1B1
	SCHEMBL6380266	0.75	PPARG (0.54)	PTPN1NPC1RAB9AFFAR1PPARG
	SCHEMBL7948992	0.75	TSHR (0.46)	NPC1RAB9A
	SCHEMBL9868496	0.75	NPC1 (0.55)	NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.