SCHEMBL17456243

SCHEMBL17456243

Oc1ccc2c(c1)-c1ccc(-c3cccc4ccccc34)cc1C2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.46
ACMSD Q8TDX5 1/20 0.46
TLR8 Q9NR97 1/20 0.46
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CA4 P22748 2/20 0.43
CA6 P23280 2/20 0.43
ESR2 Q92731 5/20 0.41
ESR1 P03372 4/20 0.41
KDM4E B2RXH2 2/20 0.41
ALDH1A1 P00352 2/20 0.41
MAPT P10636 2/20 0.41
HPGD P15428 2/20 0.41
MEN1 O00255 1/20 0.41
MPI P34949 1/20 0.41
KMT2A Q03164 1/20 0.41
HSD17B1 P14061 2/20 0.40
HSD17B2 P37059 2/20 0.40
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27950640 0.88 MAPT (0.49) MCL1ACMSDCA1CA2KDM4E
SCHEMBL29785059 0.88 MCL1 (0.47) MCL1ACMSDCA1CA2KDM4E
SCHEMBL3137217 0.88 MCL1 (0.47) MCL1ACMSDCA1CA2KDM4E
SCHEMBL4431843 0.85 MCL1 (0.45) MCL1ACMSDCA1CA2KDM4E
SCHEMBL4895432 0.85 MCL1 (0.47) MCL1ACMSDCA1CA2KDM4E
SCHEMBL29732348 0.85 MCL1 (0.47) MCL1ACMSDCA1CA2KDM4E
Ammonia Solution, Strong SCHEMBL29226614 0.80 MCL1 (0.46) MCL1ACMSDCA1CA2KDM4E
SCHEMBL21224143 0.80 MCL1 (0.43) MCL1ACMSDTLR8CA1CA2
SCHEMBL21224124 0.79 ESR2 (0.47) MCL1ACMSDTLR8CA1CA2
SCHEMBL2763754 0.78 ALDH1A1 (0.53) CA1CA2CA4CA6KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160023978-A1 6-HYDROXY-2-NAPHTHALENYL FLUORENE DERIVATIVES AND LENS AND CAMERA MODULE USING THE SAME SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) 2016-01-28 US claimed
US-20160023978-A1 6-HYDROXY-2-NAPHTHALENYL FLUORENE DERIVATIVES AND LENS AND CAMERA MODULE USING THE SAME SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) 2016-01-28 US disclosed
US-20160023978-A1 6-HYDROXY-2-NAPHTHALENYL FLUORENE DERIVATIVES AND LENS AND CAMERA MODULE USING THE SAME SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) 2016-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160023978-A1 6-HYDROXY-2-NAPHTHALENYL FLUORENE DERIVATIVES AND LENS AND CAMERA MODULE USING THE SAME SUN2, UACA, HNF4A MCL1 4812/4885ACMSD 2918/4885TLR8 1179/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.