SCHEMBL17459247

SCHEMBL17459247

Cc1cccc(N(c2ccc(N(c3ccccc3)c3cccc(-c4ccccc4)c3N(c3ccccc3)c3ccc(N(c4cccc(C)c4)c4cccc(C)c4)cc3)cc2)c2cccc(C)c2)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 2/20 0.38
L3MBTL1 Q9Y468 3/20 0.35
HSD17B1 P14061 3/20 0.34
HSD17B2 P37059 3/20 0.34
CRHR1 P34998 1/20 0.33
TSHR P16473 3/20 0.33
HPGD P15428 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
ALDH1A1 P00352 4/20 0.33
MAPT P10636 2/20 0.33
KDM4E B2RXH2 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HTT P42858 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27935316 1.00 HTR7 (0.38) HTR7L3MBTL1HSD17B1HSD17B2CRHR1
SCHEMBL3877945 0.97 HTR7 (0.39) HTR7L3MBTL1HSD17B1HSD17B2CRHR1
SCHEMBL2687221 0.90 L3MBTL1 (0.38) HTR7L3MBTL1HSD17B1HSD17B2CRHR1
SCHEMBL18042241 0.90 L3MBTL1 (0.38) HTR7L3MBTL1HSD17B1HSD17B2CRHR1
SCHEMBL1900260 0.88 HTR7 (0.38) HTR7L3MBTL1CRHR1SMN1; SMN2ALDH1A1
SCHEMBL5419249 0.88 ALDH1A1 (0.41) L3MBTL1CRHR1HPGDSMN1; SMN2ALDH1A1
SCHEMBL3443099 0.87 HTR7 (0.36) HTR7L3MBTL1HSD17B1HSD17B2CRHR1
SCHEMBL7951712 0.87 HSD17B1 (0.35) L3MBTL1HSD17B1HSD17B2CRHR1HPGD
SCHEMBL5456198 0.87 HSD17B1 (0.35) L3MBTL1HSD17B1HSD17B2CRHR1HPGD
SCHEMBL29438470 0.86 L3MBTL1 (0.39) HTR7L3MBTL1HSD17B1HSD17B2CRHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016013732-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DIODE, ORGANIC OPTOELECTRIC DIODE, AND DISPLAY DEVICE 삼성에스디아이 주식회사 2016-01-28 WO disclosed