Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 1/20 | 0.43 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | WRN | Q14191 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5246292 | 1.00 | GABBR2 (0.43) | GABBR2GABBR1CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL5247316 | 1.00 | GABBR2 (0.43) | GABBR2GABBR1CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL14709152 | 0.83 | GABBR2 (0.43) | GABBR2GABBR1CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL27911200 | 0.83 | GABBR2 (0.43) | GABBR2GABBR1CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL23258012 | 0.81 | GABBR2 (0.42) | GABBR2GABBR1CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL22585593 | 0.81 | GABBR2 (0.42) | GABBR2GABBR1CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL17459297 | 0.81 | GABBR2 (0.54) | GABBR2GABBR1CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL21722781 | 0.79 | GABBR2 (0.41) | GABBR2GABBR1CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL21722780 | 0.79 | GABBR2 (0.41) | GABBR2GABBR1CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL23521673 | 0.79 | GABBR2 (0.41) | GABBR2GABBR1CYP3A4CYP2D6SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406605-B1 | CARBAMATES OF 2-HETEROCYCLIC-1,2-ETHANEDIOLS | SK CORP (KR) | 2007-09-19 | — | — | EP | disclosed |
| US-20050065193-A1 | Carbamates of 2-heterocyclic-1,2-ethanediols | SK CORPORATION | 2005-03-24 | — | — | US | disclosed |
| US-6841569-B2 | Carbamates of 2-heterocyclic-1,2-ethanediols | SK CORPORATION (US) | 2005-01-11 | — | — | US | disclosed |
| US-20030078235-A1 | Carbamates of 2-heterocyclic-1,2-ethanediols | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2003-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065193-A1 | Carbamates of 2-heterocyclic-1,2-ethanediols | CNR2, CNR1, GRIN2C | GABBR2 21/4885GABBR1 11/4885CYP3A4 276/4885 |
| US-20030078235-A1 | Carbamates of 2-heterocyclic-1,2-ethanediols | CNR2, CNR1, GRIN2C | GABBR2 21/4885GABBR1 11/4885CYP3A4 276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.