Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.31 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17468345 | 0.84 | MAOB (0.42) | CYP19A1SLC6A2SLC6A4SLC6A3LTA4H | |
| SCHEMBL17469027 | 0.84 | MAOB (0.42) | CYP19A1SLC6A2SLC6A4SLC6A3LTA4H | |
| SCHEMBL17459303 | 0.80 | LTA4H (0.38) | SLC6A2SLC6A4SLC6A3LTA4H | |
| SCHEMBL17459409 | 0.80 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3LTA4H | |
| SCHEMBL17459287 | 0.80 | LTA4H (0.38) | SLC6A2SLC6A4SLC6A3LTA4H | |
| SCHEMBL17459277 | 0.80 | LTA4H (0.38) | SLC6A2SLC6A4SLC6A3LTA4HTSHR | |
| SCHEMBL17459309 | 0.80 | LTA4H (0.40) | CYP19A1SLC6A2SLC6A4SLC6A3LTA4H | |
| SCHEMBL17459364 | 0.79 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3ALDH1A1OPRM1 | |
| SCHEMBL17469164 | 0.78 | LTA4H (0.43) | LTA4H | |
| SCHEMBL17459470 | 0.78 | LTA4H (0.40) | SLC6A2SLC6A4SLC6A3LTA4HALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016012333-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-28 | — | — | WO | disclosed |
| WO-2016012333-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-28 | — | — | WO | disclosed |