Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | GUSB | P08236 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17469146 | 0.92 | DRD3 (0.40) | HTR2CDRD3HRH3FFAR1KIF11 | |
| SCHEMBL17469070 | 0.90 | GUSB (0.41) | KDM4EALDH1A1HPGDGUSBSLC6A2 | |
| SCHEMBL17459409 | 0.86 | SLC6A2 (0.40) | GUSBSLC6A2SLC6A4SLC6A3LTA4H | |
| SCHEMBL17459309 | 0.84 | LTA4H (0.40) | KDM4EHRH3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17469027 | 0.81 | MAOB (0.42) | DRD3KDM4EALDH1A1HPGDKIF11 | |
| SCHEMBL17468345 | 0.81 | MAOB (0.42) | DRD3KDM4EALDH1A1HPGDKIF11 | |
| SCHEMBL17469111 | 0.81 | DRD3 (0.40) | HTR2CDRD3HRH3FFAR1KIF11 | |
| SCHEMBL17469148 | 0.80 | KDM1A (0.42) | ALDH1A1PRMT5WDR77 | |
| SCHEMBL17459422 | 0.79 | LMNA (0.48) | DRD3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17469139 | 0.78 | MAOB (0.43) | SLC6A2SLC6A4SLC6A3LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016012333-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-28 | — | — | WO | disclosed |