Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | GAA | P10253 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.35 |
| ▸ | GFER | P55789 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | YWHAG | P61981 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30790657 | 0.67 | MEN1 (0.40) | ALDH1A1POLBMAPTGAAMEN1 | |
| SCHEMBL499065 | 0.64 | NOS3 (0.58) | ALDH1A1POLBDRD3 | |
| SCHEMBL8117979 | 0.63 | KMT2A (0.44) | ALDH1A1POLBMAPTGAAMEN1 | |
| SCHEMBL28770706 | 0.63 | ALDH1A1 (0.71) | ALDH1A1POLBMAPTGAAMEN1 | |
| SCHEMBL241271 | 0.62 | ALDH1A1 (0.93) | ALDH1A1POLBMAPTGAAMEN1 | |
| SCHEMBL28281987 | 0.62 | CYP19A1 (0.35) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL499955 | 0.62 | NOS3 (0.57) | ALDH1A1POLB | |
| SCHEMBL8154041 | 0.61 | ALDH1A1 (0.69) | ALDH1A1POLBMAPTGAAMEN1 | |
| SCHEMBL6156455 | 0.60 | ALDH1A1 (0.96) | ALDH1A1POLBMAPTGAAMEN1 | |
| SCHEMBL160768 | 0.60 | ALDH1A1 (1.00) | ALDH1A1POLBMAPTGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2386556-B1 | Benzothiazole cyclobutyl amine derivatives and their use as histamine-3 receptors ligands | ABBVIE INC (US) | 2013-10-23 | — | — | EP | disclosed |
| EP-2386556-A1 | Benzothiazole cyclobutyl amine derivatives and their use as histamine-3 receptors ligands | Abbott Laboratories (US) | 2011-11-16 | — | — | EP | disclosed |
| US-20110254413-A1 | CASING OF ELECTRONIC DEVICE AND MANUFACTURING METHOD THEREOF | ASUSTEK COMPUTER INC. (TW) | 2011-10-20 | — | — | US | disclosed |