Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | FGF23 | Q9GZV9 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16439215 | 0.81 | MAPK14 (0.47) | PTGS2SLC6A3FGF23ALDH1A1PTGS1 | |
| SCHEMBL1700335 | 0.81 | SLC6A3 (0.46) | PTGS2SLC6A3FGF23ALDH1A1CYP1A2 | |
| SCHEMBL16439209 | 0.80 | FGF23 (0.55) | PTGS2SLC6A3CYP2A6FGF23ALDH1A1 | |
| SCHEMBL1956409 | 0.79 | SLC6A3 (0.47) | PTGS2SLC6A3FGF23ALDH1A1HPGD | |
| SCHEMBL1957404 | 0.79 | SLC6A3 (0.47) | PTGS2SLC6A3FGF23ALDH1A1HPGD | |
| SCHEMBL1957401 | 0.79 | SLC6A3 (0.47) | PTGS2SLC6A3FGF23ALDH1A1HPGD | |
| SCHEMBL15171504 | 0.79 | CHRNB4 (0.49) | SLC6A3FGF23RAB9ASMN1; SMN2MAPT | |
| SCHEMBL3378277 | 0.78 | FGF23 (0.53) | PTGS2SLC6A3CYP2A6FGF23ALDH1A1 | |
| SCHEMBL1958644 | 0.77 | PTGS2 (0.50) | PTGS2SLC6A3FGF23ALDH1A1PTGS1 | |
| SCHEMBL502422 | 0.77 | FGF23 (0.40) | PTGS2SLC6A3FGF23ALDH1A1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3172185-B1 | SUBSTITUTED PHENYL ALKANOIC ACID COMPOUNDS AS GPR120 AGONISTS AND USES THEREOF | PIRAMAL ENTPR LTD (IN) | 2020-03-04 | — | — | EP | disclosed |
| US-10273230-B2 | Substituted phenyl alkanoic acid compounds as GPR120 agonists and uses thereof | Piramal Enterprises Limited (IN) | 2019-04-30 | — | — | US | disclosed |
| US-20170210731-A1 | SUBSTITUTED PHENYL ALKANOIC ACID COMPOUNDS AS GPR120 AGONISTS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2017-07-27 | — | — | US | disclosed |
| EP-3172185-A2 | SUBSTITUTED PHENYL ALKANOIC ACID COMPOUNDS AS GPR120 AGONISTS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2017-05-31 | — | — | EP | disclosed |
| WO-2016012965-A2 | SUBSTITUTED PHENYL ALKANOIC ACID COMPOUNDS AS GPR120 AGONISTS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2016-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170210731-A1 | SUBSTITUTED PHENYL ALKANOIC ACID COMPOUNDS AS GPR120 AGONISTS AND USES THEREOF | FFAR1, FFAR3, GPR55 | PTGS2 679/4885SLC6A3 728/4885CYP2A6 697/4885 |
| US-10273230-B2 | Substituted phenyl alkanoic acid compounds as GPR120 agonists and uses thereof | FFAR1, FFAR3, GPR55 | PTGS2 679/4885SLC6A3 728/4885CYP2A6 697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.