SCHEMBL17463229

SCHEMBL17463229

N#Cc1ccc(N(c2ccccc2)c2cccc([Si](c3ccccc3)(c3ccccc3)c3ccc4c(c3)c3ccccc3n4-c3ccccc3)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.38
KDM4E B2RXH2 2/20 0.38
ATM Q13315 1/20 0.38
RORC P51449 9/20 0.37
PTGER4 P35408 2/20 0.33
USP14 P54578 2/20 0.32
PER2 O15055 2/20 0.31
CRY1 Q16526 2/20 0.31
CRY2 Q49AN0 2/20 0.31
ALDH1A1 P00352 2/20 0.31
USP2 O75604 1/20 0.31
LMNA P02545 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
CASP1 P29466 1/20 0.30
HSD17B10 Q99714 1/20 0.30
ABCG2 Q9UNQ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17463227 0.97 KDM4E (0.40) L3MBTL1KDM4EATMRORCPTGER4
SCHEMBL12721976 0.96 RORC (0.40) L3MBTL1KDM4EATMRORCPTGER4
SCHEMBL17463228 0.96 KDM4E (0.41) L3MBTL1KDM4EATMRORCPTGER4
SCHEMBL12721697 0.94 RORC (0.35) L3MBTL1KDM4EATMRORCUSP14
SCHEMBL22907672 0.93 KDM4E (0.35) L3MBTL1KDM4EATMRORCPTGER4
SCHEMBL22907466 0.93 KDM4E (0.35) L3MBTL1KDM4EATMRORCPTGER4
SCHEMBL13249692 0.92 RORC (0.35) L3MBTL1KDM4EATMRORCUSP14
SCHEMBL17463223 0.90 KDM4E (0.46) L3MBTL1KDM4EATMPTGER4ALDH1A1
SCHEMBL12722017 0.90 RORC (0.36) L3MBTL1KDM4EATMRORCPTGER4
SCHEMBL12721995 0.90 RORC (0.36) L3MBTL1KDM4EATMRORCPTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160028030-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD., (KR) 2016-01-28 US disclosed
US-20160028030-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD., (KR) 2016-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160028030-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CCNE2, CCNE1 L3MBTL1 863/4885KDM4E 1882/4885ATM 1164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.