SCHEMBL13249692

SCHEMBL13249692

N#Cc1ccc(N(c2ccc3c(c2)c2cc([Si](c4ccccc4)(c4ccccc4)c4ccccc4)ccc2n3-c2ccccc2)c2ccc3c(c2)c2cc([Si](c4ccccc4)(c4ccccc4)c4ccccc4)ccc2n3-c2ccccc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RORC P51449 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.33
KDM4E B2RXH2 1/20 0.33
ATM Q13315 1/20 0.33
TDP2 O95551 3/20 0.32
USP2 O75604 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
ABCG2 Q9UNQ0 1/20 0.31
G6PD P11413 2/20 0.30
USP14 P54578 2/20 0.30
HPGD P15428 1/20 0.30
PDE10A Q9Y233 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12721697 0.99 RORC (0.35) RORCL3MBTL1KDM4EATMTDP2
SCHEMBL12721976 0.97 RORC (0.40) RORCL3MBTL1KDM4EATMTDP2
SCHEMBL12721724 0.95 RORC (0.35) RORCL3MBTL1TDP2USP2ALDH1A1
SCHEMBL12721741 0.95 PTGDR2 (0.35) RORCKDM4ETDP2USP14
SCHEMBL17463228 0.94 KDM4E (0.41) RORCL3MBTL1KDM4EATMTDP2
SCHEMBL13249739 0.93 GABRA1 (0.34) RORCABCG2USP14
SCHEMBL17463227 0.93 KDM4E (0.40) RORCL3MBTL1KDM4EATMTDP2
SCHEMBL13249700 0.92 RORC (0.35) RORCL3MBTL1KDM4EUSP2ALDH1A1
SCHEMBL13249709 0.92 PGR (0.36) RORCKDM4ETDP2USP14
SCHEMBL17463229 0.92 L3MBTL1 (0.38) RORCL3MBTL1KDM4EATMUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7754349-B2 Silanylamine-based compound and organic light-emitting device including organic layer including the silanylamine-based compound SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2010-07-13 US disclosed
US-20080171227-A1 SILANYLAMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANIC LAYER INCLUDING THE SILANYLAMINE-BASED COMPOUND SAMSUNG SDI CO., LTD. (KR) 2008-07-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080171227-A1 SILANYLAMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANIC LAYER INCLUDING THE SILANYLAMINE-BASED COMPOUND ADRB2, ADRB1, ADRB3 RORC 1290/4885L3MBTL1 841/4885KDM4E 2582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.