SCHEMBL1746441

SCHEMBL1746441

CCCC[Si](C)(C)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.44
▸ MAPT P10636 1/20 0.43
▸ CETP P11597 1/20 0.42
▸ MAPK1 P28482 1/20 0.41
▸ GAA P10253 1/20 0.40
▸ TYR P14679 1/20 0.40
▸ POLB P06746 1/20 0.40
▸ PTPN1 P18031 1/20 0.39
▸ SYNJ2 O15056 1/20 0.39
▸ GJB2 P29033 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14939003 1.00 L3MBTL1 (0.44) L3MBTL1MAPTCETPMAPK1GAA
SCHEMBL17651845 1.00 L3MBTL1 (0.44) L3MBTL1MAPTCETPMAPK1GAA
SCHEMBL1747620 1.00 L3MBTL1 (0.44) L3MBTL1MAPTCETPMAPK1GAA
SCHEMBL13157184 1.00 L3MBTL1 (0.44) L3MBTL1MAPTCETPMAPK1GAA
SCHEMBL5309010 1.00 L3MBTL1 (0.44) L3MBTL1MAPTCETPMAPK1GAA
SCHEMBL1746034 0.94 CETP (0.46) L3MBTL1MAPTCETPMAPK1GAA
SCHEMBL13157186 0.94 CETP (0.46) L3MBTL1MAPTCETPMAPK1GAA
SCHEMBL1745771 0.94 CETP (0.46) L3MBTL1MAPTCETPMAPK1GAA
SCHEMBL13157187 0.94 CETP (0.46) L3MBTL1MAPTCETPMAPK1GAA
SCHEMBL1746439 0.80 OGA (0.37) MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007048974-A2 D-GLUCOSAMINE AND N-ACETYL-D-GLUCOSAMINE HETEROOLIGOMERS, METHOD FOR PREPARING SAME AND USE THEREOF UNIVERSITE CLAUDE BERNARD LYON I (FR) 2007-05-03 — — WO claimed
WO-2020232194-A1 METHODS FOR GLYCOSYLATION THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2020-11-19 — — WO disclosed
EP-2563337-B1 CARRIER AND TARGETING SYSTEM COMPRISING A SIOSOMAL COMPOSITION FOR INTRACELLULAR DELIVERY AND TARGETING OF ACTIVE SUBSTANCE SALAMA ZOSER B (DE) 2017-07-26 — — EP disclosed
EP-2776449-A2 PROCESS FOR THE PREPARATION OF beta-C-ARYL GLUCOSIDES Scinopharm Taiwan Ltd. (TW) 2014-09-17 — — EP disclosed
WO-2013068850-A2 PROCESS FOR THE PREPARATION OF β-C-ARYL GLUCOSIDES SCINOPHARM TAIWAN, LTD. (NA) 2013-05-16 — — WO disclosed
EP-2384743-A1 Siosomal formulation for intracellular delivery and targeting of therapeutic agents Salama, Zoser B. (DE) 2011-11-09 — — EP disclosed
WO-2007048974-A2 D-GLUCOSAMINE AND N-ACETYL-D-GLUCOSAMINE HETEROOLIGOMERS, METHOD FOR PREPARING SAME AND USE THEREOF UNIVERSITE CLAUDE BERNARD LYON I (FR) 2007-05-03 — — WO disclosed
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