SCHEMBL13157184

SCHEMBL13157184

CCCC[Si](C)(C)OC1OC(CO)C(O)C(O)C1O

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.44
▸ MAPT P10636 1/20 0.43
▸ CETP P11597 1/20 0.42
▸ MAPK1 P28482 1/20 0.41
▸ GAA P10253 1/20 0.40
▸ TYR P14679 1/20 0.40
▸ POLB P06746 1/20 0.40
▸ PTPN1 P18031 1/20 0.39
▸ SYNJ2 O15056 1/20 0.39
▸ GJB2 P29033 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1746441 1.00 L3MBTL1 (0.44) L3MBTL1MAPTCETPMAPK1GAA
SCHEMBL14939003 1.00 L3MBTL1 (0.44) L3MBTL1MAPTCETPMAPK1GAA
SCHEMBL17651845 1.00 L3MBTL1 (0.44) L3MBTL1MAPTCETPMAPK1GAA
SCHEMBL1747620 1.00 L3MBTL1 (0.44) L3MBTL1MAPTCETPMAPK1GAA
SCHEMBL5309010 1.00 L3MBTL1 (0.44) L3MBTL1MAPTCETPMAPK1GAA
SCHEMBL1746034 0.94 CETP (0.46) L3MBTL1MAPTCETPMAPK1GAA
SCHEMBL13157186 0.94 CETP (0.46) L3MBTL1MAPTCETPMAPK1GAA
SCHEMBL1745771 0.94 CETP (0.46) L3MBTL1MAPTCETPMAPK1GAA
SCHEMBL13157187 0.94 CETP (0.46) L3MBTL1MAPTCETPMAPK1GAA
SCHEMBL1746439 0.80 OGA (0.37) MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100247578-A1 CARRIER SYSTEM FOR BIOLOGICAL AGENTS CONTAINING ORGANOSILICON COMPOUNDS AND USES THEREOF SALAMA ZOSER B 2010-09-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100247578-A1 CARRIER SYSTEM FOR BIOLOGICAL AGENTS CONTAINING ORGANOSILICON COMPOUNDS AND USES THEREOF EXOSC5, EXOSC9, SSB L3MBTL1 3820/4885MAPT 1855/4885CETP 601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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