Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17464881 | 0.80 | TSHR (0.43) | TSHRLMNATDP1 | |
| SCHEMBL17464931 | 0.74 | TDP1 (0.33) | TSHRTDP1 | |
| SCHEMBL18759644 | 0.74 | TSHR (0.35) | TSHRLMNATDP1 | |
| SCHEMBL8403161 | 0.73 | SMN1; SMN2 (0.36) | TSHRLMNAALDH1A1 | |
| SCHEMBL3621633 | 0.73 | TSHR (0.47) | TSHRTDP1ALDH1A1 | |
| SCHEMBL11746732 | 0.72 | TSHR (0.33) | TSHRLMNATDP1 | |
| SCHEMBL17468043 | 0.70 | TSHR (0.36) | TSHRLMNA | |
| SCHEMBL713526 | 0.70 | TSHR (0.38) | TSHRLMNA | |
| SCHEMBL16074672 | 0.68 | TSHR (0.36) | TSHRLMNATDP1ALDH1A1 | |
| SCHEMBL28477505 | 0.68 | TSHR (0.35) | TSHRLMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9550763-B2 | Heterocyclic ring and carbocyclic derivative | SHIONOGI & CO., LTD. (JP) | 2017-01-24 | — | — | US | disclosed |
| US-20160024072-A1 | Heterocyclic Ring and Carbocyclic Derivative | SHIONOGI & CO., LTD. (JP) | 2016-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160024072-A1 | Heterocyclic Ring and Carbocyclic Derivative | P2RX3, P2RX7, P2RX2 | TSHR 737/4885LMNA 3635/4885TDP1 4738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.