Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 3/20 | 0.33 |
| ▸ | GABRD | O14764 | 3/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.33 |
| ▸ | GABRE | P78334 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17467128 | 0.78 | GABRP (0.39) | MEN1KMT2ANOS1NOS3HTT | |
| SCHEMBL16227532 | 0.78 | L3MBTL1 (0.40) | MEN1KMT2AL3MBTL1CD274PDCD1 | |
| SCHEMBL18422978 | 0.76 | MEN1 (0.33) | MEN1KMT2AHTTL3MBTL1KDM4E | |
| SCHEMBL17467131 | 0.75 | SLC13A5 (0.37) | MEN1KMT2AHTTL3MBTL1KDM4E | |
| SCHEMBL15544881 | 0.71 | CD274 (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL5645549 | 0.70 | ALDH1A1 (0.42) | KDM4EHSD17B10POLBALDH1A1TSHR | |
| SCHEMBL17467146 | 0.70 | ACLY (0.39) | MEN1KMT2AHTTKDM4EALDH1A1 | |
| SCHEMBL1845830 | 0.70 | MEN1 (0.52) | MEN1KMT2AHTTL3MBTL1TDP1 | |
| SCHEMBL15544883 | 0.69 | GABRP (0.39) | MEN1KMT2AL3MBTL1KDM4EGABRP | |
| SCHEMBL2340705 | 0.69 | MEN1 (0.46) | MEN1KMT2AHTTL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9249160-B2 | Orexin receptor antagonists | HEPTARES THERAPEUTICS LIMITED (GB) | 2016-02-02 | — | — | US | disclosed |