Sugi Predict

Sugi Predict / Compounds / SCHEMBL17467640

SCHEMBL17467640

SCHEMBL17467640

CC(C)C1CCC2(CC1)OCCCO2

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ MMP1 P03956 1/20 0.34
▸ MMP2 P08253 1/20 0.34
▸ MMP3 P08254 1/20 0.34
▸ MMP7 P09237 1/20 0.34
▸ MMP13 P45452 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8275624 0.91 CTSS (0.31) —
SCHEMBL22252311 0.78 KCNH2 (0.30) —
SCHEMBL21238556 0.78 KCNH2 (0.30) —
SCHEMBL17467614 0.78 KCNH2 (0.30) —
SCHEMBL23344177 0.78 — —
SCHEMBL21960463 0.78 — —
SCHEMBL21948711 0.78 — —
SCHEMBL14671049 0.77 — —
SCHEMBL25966814 0.77 HSD11B1 (0.31) —
SCHEMBL21042857 0.76 MMP1 (0.30) MMP1MMP2MMP3MMP7MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210078951-A1 ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF Epizyme, Inc. 2021-03-18 — — US disclosed
US-10800743-B2 Arginine methyltransferase inhibitors and uses thereof Epizyme, Inc. (US) 2020-10-13 — — US disclosed
US-20190100496-A1 ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF Epizyme, Inc. 2019-04-04 — — US disclosed
US-20170267642-A1 ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF Epizyme, Inc. (US) 2017-09-21 — — US disclosed
US-20170267642-A1 ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF Epizyme, Inc. (US) 2017-09-21 — — US disclosed
US-9598374-B2 Arginine methyltransferase inhibitors and uses thereof Epizyme, Inc. (US) 2017-03-21 — — US disclosed
US-9598374-B2 Arginine methyltransferase inhibitors and uses thereof Epizyme, Inc. (US) 2017-03-21 — — US disclosed
US-20160024016-A1 ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF Epizyme, Inc. (US) 2016-01-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10800743-B2 Arginine methyltransferase inhibitors and uses thereof PRMT1, PRMT3, PRMT5 MMP1 3168/4885MMP2 1568/4885MMP3 2231/4885
US-20210078951-A1 ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF PRMT1, PRMT3, PRMT5 MMP1 3168/4885MMP2 1568/4885MMP3 2231/4885
US-20170267642-A1 ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF PRMT1, PRMT3, PRMT5 MMP1 3168/4885MMP2 1568/4885MMP3 2231/4885
US-20190100496-A1 ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF PRMT1, PRMT3, PRMT5 MMP1 3168/4885MMP2 1568/4885MMP3 2231/4885
US-20160024016-A1 ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF PRMT1, PRMT3, PRMT5 MMP1 3168/4885MMP2 1568/4885MMP3 2231/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.