Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 3/20 | 0.46 |
| ▸ | ADH1B | P00325 | 1/20 | 0.44 |
| ▸ | ADH1C | P00326 | 1/20 | 0.44 |
| ▸ | ADH1A | P07327 | 1/20 | 0.44 |
| ▸ | ADH7 | P40394 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4406338 | 0.83 | DRD4 (0.58) | MEN1KMT2ATDP1DRD4MAOA | |
| SCHEMBL6660880 | 0.81 | DRD4 (0.56) | MEN1KMT2ATDP1DRD4MAOA | |
| SCHEMBL18022724 | 0.81 | KDM4E (0.51) | MEN1KMT2ATDP1DRD4ADH1B | |
| SCHEMBL17467938 | 0.79 | KMT2A (0.47) | MEN1KMT2ATDP1ADH1BADH1C | |
| SCHEMBL2368549 | 0.77 | ALDH1A1 (0.48) | MEN1KMT2ATDP1MAOASMN1; SMN2 | |
| SCHEMBL9165276 | 0.76 | DNM1 (0.48) | MEN1KMT2A | |
| SCHEMBL18966695 | 0.76 | TDP1 (0.52) | MEN1KMT2ATDP1DRD4ADH1B | |
| SCHEMBL2368921 | 0.75 | EPHX2 (0.50) | MAOACHRM2KDM4EPKM | |
| SCHEMBL11613615 | 0.75 | KMT2A (0.61) | MEN1KMT2ASMN1; SMN2GAAMAPT | |
| Hydrochloric Acid SCHEMBL7758891 | 0.74 | MEN1 (0.50) | MEN1KMT2ATDP1DRD4MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016011930-A1 | COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2016-01-28 | — | — | WO | disclosed |