SCHEMBL17469144

SCHEMBL17469144

CCN1Cc2ccccc2OC(c2ccc(-c3ccoc3)cc2)C1

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 15/20 0.34
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
DRD2 P14416 1/20 0.32
MAOB P27338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17459309 0.88 LTA4H (0.40) LTA4HSLC6A2SLC6A4SLC6A3MAOB
SCHEMBL17469139 0.85 MAOB (0.43) LTA4HSLC6A2SLC6A4SLC6A3MAOB
SCHEMBL17469070 0.85 GUSB (0.41) LTA4HSLC6A2SLC6A4SLC6A3
SCHEMBL17469165 0.83 MAOB (0.47) LTA4HSLC6A4MAOB
SCHEMBL17469027 0.83 MAOB (0.42) LTA4HSLC6A2SLC6A4SLC6A3MAOB
SCHEMBL17468345 0.83 MAOB (0.42) LTA4HSLC6A2SLC6A4SLC6A3MAOB
SCHEMBL17469138 0.82 DRD2 (0.36) LTA4HDRD2
SCHEMBL17459303 0.81 LTA4H (0.38) LTA4HSLC6A2SLC6A4SLC6A3MAOB
SCHEMBL17459287 0.81 LTA4H (0.38) LTA4HSLC6A2SLC6A4SLC6A3MAOB
SCHEMBL17459409 0.81 SLC6A2 (0.40) LTA4HSLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016012333-A1 PESTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2016-01-28 WO disclosed