Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17469641 | 0.88 | KIT (0.47) | KITFLT3NTRK3F2 | |
| SCHEMBL17469662 | 0.82 | KIT (0.40) | KITFLT3NTRK3F2LMNA | |
| SCHEMBL17469637 | 0.78 | KIT (0.72) | KITFLT3NTRK3F2SMN1; SMN2 | |
| SCHEMBL17469797 | 0.72 | CCNC (0.45) | — | |
| SCHEMBL17469875 | 0.67 | FLT3 (0.41) | KITFLT3NTRK3F2 | |
| SCHEMBL21103816 | 0.66 | KIT (0.47) | KITFLT3NTRK3 | |
| SCHEMBL17469655 | 0.65 | KIT (0.79) | KITFLT3NTRK3F2 | |
| SCHEMBL17469644 | 0.63 | FLT3 (0.78) | KITFLT3NTRK3F2 | |
| SCHEMBL19532040 | 0.63 | KIT (0.46) | KITFLT3NTRK3HTT | |
| SCHEMBL30003784 | 0.63 | KIT (0.46) | KITFLT3NTRK3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016014674-A1 | LINKED DIARYL COMPOUNDS WITH ANTICANCER PROPERTIES AND METHODS OF USING THE SAME | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2016-01-28 | — | — | WO | disclosed |