SCHEMBL1747692

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12844796	0.84	L3MBTL1 (0.40)	FAAHL3MBTL1ATMCYP1A2GAA
	SCHEMBL350463	0.80	AKR1C3 (0.61)	AKR1C3AKR1C2CYP2C9CYP2C19DGAT1
	SCHEMBL19182818	0.80	L3MBTL1 (0.56)	L3MBTL1ATMMEN1KMT2AGAA
	SCHEMBL155788	0.80	L3MBTL1 (0.56)	L3MBTL1ATMMEN1KMT2AGAA
	Formaldehyde SCHEMBL27761906	0.77	L3MBTL1 (0.53)	L3MBTL1ATMMEN1KMT2AGAA
	SCHEMBL28465915	0.76	KDM4E (0.46)	FAAHL3MBTL1ATMMEN1KMT2A
	SCHEMBL28465913	0.76	KDM4E (0.46)	FAAHL3MBTL1ATMMEN1KMT2A
	SCHEMBL16751892	0.72	AKR1C3 (0.49)	AKR1C3AKR1C2L3MBTL1CYP3A4CYP2D6
	SCHEMBL16751911	0.71	DGAT1 (0.47)	AKR1C3AKR1C2L3MBTL1CYP3A4MEN1
	SCHEMBL12844795	0.71	AKR1C3 (0.44)	AKR1C3AKR1C2L3MBTL1CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.