Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.35 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12844892 | 0.83 | GAA (0.31) | AKR1C3AKR1C2 | |
| SCHEMBL350463 | 0.80 | AKR1C3 (0.61) | AKR1C3AKR1C2ALDH1A1NAPRTDGAT1 | |
| SCHEMBL1747703 | 0.78 | AKR1C3 (0.42) | AKR1C3AKR1C2ALDH1A1NAPRTDGAT1 | |
| SCHEMBL12844799 | 0.73 | AKR1C3 (0.38) | AKR1C3AKR1C2ALDH1A1DGAT1FFAR2 | |
| SCHEMBL27801799 | 0.72 | NAPRT (0.42) | AKR1C3AKR1C2ALDH1A1NAPRTDGAT1 | |
| SCHEMBL16751892 | 0.72 | AKR1C3 (0.49) | AKR1C3AKR1C2ALDH1A1NAPRTDGAT1 | |
| SCHEMBL1747692 | 0.71 | AKR1C3 (0.44) | AKR1C3AKR1C2ALDH1A1DGAT1MAPT | |
| SCHEMBL13359679 | 0.71 | AKR1C3 (0.40) | AKR1C3AKR1C2DGAT1MAPTRAB9A | |
| SCHEMBL8924164 | 0.70 | LMNA (0.45) | AKR1C3AKR1C2ALDH1A1NAPRTDGAT1 | |
| SCHEMBL20096396 | 0.69 | DGAT1 (0.41) | AKR1C3AKR1C2ALDH1A1DGAT1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7902233-B2 | Compounds useful as pesticides | DOW AGROSCIENCES LLC (US) | 2011-03-08 | — | — | US | disclosed |
| US-20090318466-A1 | COMPOUNDS USEFUL AS PESTICIDES | DOW AGROSCIENCES LLC (US) | 2009-12-24 | — | — | US | disclosed |
| US-7557132-B2 | Compounds useful as pesticides | DOW AGROSCIENCES LLC (US) | 2009-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318466-A1 | COMPOUNDS USEFUL AS PESTICIDES | DDT, ACHE, BCHE | AKR1C3 2453/4885AKR1C2 2544/4885ALDH1A1 2675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.