SCHEMBL1747703

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL350463	0.78	AKR1C3 (0.61)	AKR1C3AKR1C2ALDH1A1NAPRTFFAR2
	SCHEMBL12844795	0.78	AKR1C3 (0.44)	AKR1C3AKR1C2ALDH1A1MAPTNAPRT
	SCHEMBL1747750	0.74	AKR1C3 (0.37)	AKR1C3AKR1C2CASP6NPC1ALDH1A1
	SCHEMBL1747749	0.74	AKR1C3 (0.37)	AKR1C3AKR1C2CASP6NPC1ALDH1A1
	SCHEMBL1747747	0.74	AKR1C3 (0.37)	AKR1C3AKR1C2CASP6NPC1ALDH1A1
	SCHEMBL9864824	0.74	AKR1C3 (0.39)	AKR1C3AKR1C2CASP6NPC1ALDH1A1
	SCHEMBL30353352	0.71	ALDH1A1 (0.54)	CASP6ALDH1A1MAPTNAPRTCYP2D6
	SCHEMBL25556165	0.71	ALDH1A1 (0.54)	CASP6ALDH1A1MAPTNAPRTCYP2D6
	SCHEMBL27801799	0.70	NAPRT (0.42)	AKR1C3AKR1C2ALDH1A1MAPTNAPRT
	SCHEMBL4410557	0.70	CASP6 (0.34)	AKR1C3AKR1C2FAAHCASP6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.