Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.38 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.38 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2178791 | 0.82 | ALDH1A1 (0.50) | MEN1KMT2AALOX12ALDH1A1GPR35 | |
| SCHEMBL30557784 | 0.82 | ALDH1A1 (0.50) | MEN1KMT2AALOX12ALDH1A1GPR35 | |
| SCHEMBL29001447 | 0.81 | TDP1 (0.49) | MEN1KMT2AALOX12ALDH1A1GPR35 | |
| SCHEMBL30350882 | 0.81 | TDP1 (0.49) | MEN1KMT2AALOX12ALDH1A1GPR35 | |
| SCHEMBL17477195 | 0.80 | POLB (0.41) | MEN1KMT2AALDH1A1HPGDTSHR | |
| SCHEMBL845293 | 0.77 | TDP1 (0.41) | MEN1KMT2AALDH1A1GPR35MAPK1 | |
| SCHEMBL202616 | 0.77 | ADRA2A (0.55) | HSPB1MEN1KMT2AALOX12ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28280779 | 0.75 | ADRA2A (0.56) | HSPB1MEN1KMT2AALOX12ALDH1A1 | |
| SCHEMBL14659678 | 0.72 | ALDH1A1 (0.44) | HSPB1MEN1KMT2AALOX12ALDH1A1 | |
| SCHEMBL457895 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170218007-A1 | A PROCESS FOR THE PREPARATION OF NUCLEOSIDE PHOSPHORAMIDATE | LUPIN LIMITED (IN) | 2017-08-03 | — | — | US | disclosed |
| EP-3174888-A1 | A PROCESS FOR THE PREPARATION OF NUCLEOSIDE PHOSPHORAMIDATE | Lupin Limited (IN) | 2017-06-07 | — | — | EP | disclosed |
| WO-2016016865-A1 | A PROCESS FOR THE PREPARATION OF NUCLEOSIDE PHOSPHORAMIDATE | LUPIN LIMITED (IN) | 2016-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170218007-A1 | A PROCESS FOR THE PREPARATION OF NUCLEOSIDE PHOSPHORAMIDATE | SAMHD1, PNP, MTAP | HSPB1 4271/4885MEN1 4174/4885KMT2A 2963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.