Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 6/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30557784 | 1.00 | ALDH1A1 (0.50) | ALDH1A1GPR35MAPK1TDP1HPGD | |
| SCHEMBL30350882 | 0.98 | TDP1 (0.49) | ALDH1A1GPR35MAPK1TDP1HPGD | |
| SCHEMBL29001447 | 0.98 | TDP1 (0.49) | ALDH1A1GPR35MAPK1TDP1HPGD | |
| SCHEMBL2405141 | 0.82 | ALDH1A1 (0.47) | ALDH1A1GPR35MAPK1TDP1HPGD | |
| SCHEMBL17477185 | 0.82 | HSPB1 (0.44) | ALDH1A1GPR35MAPK1TDP1HPGD | |
| SCHEMBL27579425 | 0.82 | ALDH1A1 (0.47) | ALDH1A1GPR35MAPK1TDP1HPGD | |
| SCHEMBL14659678 | 0.80 | ALDH1A1 (0.44) | ALDH1A1GPR35MAPK1TDP1HPGD | |
| SCHEMBL8078061 | 0.79 | ALDH1A1 (0.53) | ALDH1A1GPR35MAPK1TDP1HPGD | |
| SCHEMBL9942575 | 0.78 | HSP90AA1 (0.39) | ALDH1A1GPR35MAPK1TDP1HPGD | |
| SCHEMBL3146522 | 0.78 | GPR35 (0.44) | ALDH1A1GPR35MAPK1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170218007-A1 | A PROCESS FOR THE PREPARATION OF NUCLEOSIDE PHOSPHORAMIDATE | LUPIN LIMITED (IN) | 2017-08-03 | — | — | US | claimed |
| EP-3174888-A1 | A PROCESS FOR THE PREPARATION OF NUCLEOSIDE PHOSPHORAMIDATE | Lupin Limited (IN) | 2017-06-07 | — | — | EP | claimed |
| WO-2016016865-A1 | A PROCESS FOR THE PREPARATION OF NUCLEOSIDE PHOSPHORAMIDATE | LUPIN LIMITED (IN) | 2016-02-04 | — | — | WO | claimed |
| US-9123660-B2 | Chemical mechanical polishing slurry compositions and polishing method using the same | CHEIL INDUSTRIES INC. (KR) | 2015-09-01 | — | — | US | claimed |
| US-20120282775-A1 | Chemical Mechanical Polishing Slurry Compositions and Polishing Method Using the Same | CHEIL INDUSTRIES INC. (KR) | 2012-11-08 | — | — | US | claimed |
| CN-102666771-A | Cmp slurry compositions and polishing method using the same | CHEIL IND INC | 2012-09-12 | — | — | CN | claimed |
| WO-2011081503-A2 | CHEMICAL MECHANICAL POLISHING SLURRY COMPOSITIONS AND POLISHING METHOD USING THE SAME | CHEIL INDUSTRIES INC. (KR) | 2011-07-07 | — | — | WO | claimed |
| JP-6220019-A | — | — | None | — | — | JP | disclosed |
| US-20210139484-A1 | DIHYDROISOQUINOLINE-2(1H)-CARBOXAMIDE AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | GOSSAMER BIO SERVICES INC (US) | 2021-05-13 | — | — | US | disclosed |
| WO-2019200120-A1 | DIHYDROISOQUINOLINE-2(1H)-CARBOXAMIDE AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | LYCERA CORPORATION (US) | 2019-10-17 | — | — | WO | disclosed |
| US-20170218007-A1 | A PROCESS FOR THE PREPARATION OF NUCLEOSIDE PHOSPHORAMIDATE | LUPIN LIMITED (IN) | 2017-08-03 | — | — | US | disclosed |
| EP-3174888-A1 | A PROCESS FOR THE PREPARATION OF NUCLEOSIDE PHOSPHORAMIDATE | Lupin Limited (IN) | 2017-06-07 | — | — | EP | disclosed |
| WO-2016016865-A1 | A PROCESS FOR THE PREPARATION OF NUCLEOSIDE PHOSPHORAMIDATE | LUPIN LIMITED (IN) | 2016-02-04 | — | — | WO | disclosed |
| US-20050107422-A1 | Tetrahydropyranyl cyclopentyl tetrahydropyridopyridine modulators of chemokine receptor activity | MERCK SHARP & DOHME LLC | 2005-05-19 | — | — | US | disclosed |
| US-20050101628-A1 | Tetrahydropyranyl cyclopentyl tetrahydropyridopyridine modulators of chemokine receptor activity | MERCK SHARP & DOHME LLC | 2005-05-12 | — | — | US | disclosed |
| EP-1501507-A2 | TETRAHYDROPYRANYL CYCLOPENTYL TETRAHYDROPYRIDOPYRIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Merck & Co., Inc. (US) | 2005-02-02 | — | — | EP | disclosed |
| US-6812234-B2 | CCR-2; INFLAMMATORY, IMMUNOREGULATORY, ALLERGIC, AND AUTOIMMUNE DISORDERS AND DISEASES | MERCK & CO., INC. | 2004-11-02 | — | — | US | disclosed |
| US-20040167156-A1 | TETRAHYDROPYRANYL CYCLOPENTYL TETRAHYDROPYRIDOPYRIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK SHARP & DOHME LLC | 2004-08-26 | — | — | US | disclosed |
| WO-2003092586-A2 | TETRAHYDROPYRANYL CYCLOPENTYL TETRAHYDROPYRIDOPYRIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO., INC. (US) | 2003-11-13 | — | — | WO | disclosed |
| JP-H06220019-A | PRODUCTION OF 2-HYDROXY-3,5-DINITROPYRIDINE COMPOUNDS | KOEI CHEM CO LTD | 1994-08-09 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139484-A1 | DIHYDROISOQUINOLINE-2(1H)-CARBOXAMIDE AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | ULK1, PHKG2, PHKG1 | ALDH1A1 2060/4885GPR35 1752/4885MAPK1 896/4885 |
| US-20050107422-A1 | Tetrahydropyranyl cyclopentyl tetrahydropyridopyridine modulators of chemokine receptor activity | CCR1, CCR9, CCR2 | ALDH1A1 2141/4885GPR35 96/4885MAPK1 1078/4885 |
| US-20050101628-A1 | Tetrahydropyranyl cyclopentyl tetrahydropyridopyridine modulators of chemokine receptor activity | CCR2, CCR9, CCR1 | ALDH1A1 2240/4885GPR35 83/4885MAPK1 765/4885 |
| US-20040167156-A1 | TETRAHYDROPYRANYL CYCLOPENTYL TETRAHYDROPYRIDOPYRIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | CCR1, CCRL2, CCR5 | ALDH1A1 1905/4885GPR35 92/4885MAPK1 578/4885 |
| US-20170218007-A1 | A PROCESS FOR THE PREPARATION OF NUCLEOSIDE PHOSPHORAMIDATE | SAMHD1, PNP, MTAP | ALDH1A1 2758/4885GPR35 4597/4885MAPK1 3345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.