Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 6/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.36 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19066133 | 0.85 | ALDH1A1 (0.46) | LIPEGAAALDH1A1POLB | |
| SCHEMBL17477123 | 0.83 | HDAC1 (0.41) | SCN9ASCN10AHRH4TP53MDM2 | |
| SCHEMBL4336868 | 0.80 | GAA (0.60) | HRH4TP53GAAALDH1A1REN | |
| SCHEMBL25313933 | 0.78 | ALDH1A1 (0.59) | LIPEGAAALDH1A1POLB | |
| SCHEMBL22635853 | 0.77 | L3MBTL1 (0.47) | SCN9AGAAALDH1A1POLB | |
| SCHEMBL19066192 | 0.76 | ALDH1A1 (0.67) | LIPEGAAALDH1A1POLB | |
| SCHEMBL4629620 | 0.75 | HRH4 (0.40) | SCN9ASCN10AHRH4TP53MDM2 | |
| SCHEMBL18191790 | 0.73 | DPP4 (0.41) | TRPC6 | |
| SCHEMBL28384237 | 0.73 | HRH4 (0.39) | SCN9ASCN10AHRH4TP53MDM2 | |
| SCHEMBL31112011 | 0.73 | MLNR (0.50) | HRH4GAAALDH1A1REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016015605-A1 | COMPOUNDS AS CDK SMALL-MOLECULE INHIBITORS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-02-04 | — | — | WO | disclosed |