Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | REN | P00797 | 1/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16825931 | 0.85 | REN (0.53) | GAARENNPC1RAB9AKMT2A | |
| SCHEMBL31112011 | 0.84 | MLNR (0.50) | GAARENHRH4MGLLSMN1; SMN2 | |
| SCHEMBL2583030 | 0.81 | GAA (0.61) | GAANPC1RAB9AKMT2AMEN1 | |
| SCHEMBL4629620 | 0.81 | HRH4 (0.40) | GAARENHRH4ALDH1A1TP53 | |
| SCHEMBL17477186 | 0.80 | SCN9A (0.42) | GAARENHRH4ALDH1A1TP53 | |
| SCHEMBL13490134 | 0.79 | HTR2C (0.58) | HRH4NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL2579734 | 0.79 | HTR2C (0.58) | HRH4NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL2787453 | 0.79 | HTR2C (0.58) | HRH4NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL28137106 | 0.79 | GAA (0.82) | GAANPC1RAB9AKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL31066472 | 0.78 | HTR2C (0.56) | HRH4NPC1RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7569690-B2 | Process for producing oxycarbonyl-substituted piperazine derivative | TORAY FINE CHEMICALS CO., LTD. (JP) | 2009-08-04 | — | — | US | disclosed |
| CN-101107226-A | Phenoxyacetic acid derivatives useful for treating respiratory diseases | ASTRAZENECA AB (SE) | 2008-01-16 | — | — | CN | disclosed |
| CN-100360510-C | Process for producing oxycarbonyl-substituted piperazine derivative | TORAY FINECHEMICALS CO LTD (JP) | 2008-01-09 | — | — | CN | disclosed |
| US-20060161003-A1 | Process for producing oxycarbonyl-substituted piperazine derivative | TORAY FINE CHEMICALS CO., LTD. (JP) | 2006-07-20 | — | — | US | disclosed |
| CN-1681797-A | Process for producing oxycarbonyl-substituted piperazine derivative | TORAY FINECHEMICALS CO LTD (JP) | 2005-10-12 | — | — | CN | disclosed |
| EP-1548010-A1 | PROCESS FOR PRODUCING OXYCARBONYL-SUBSTITUTED PIPERAZINE DERIVATIVE | Toray Fine Chemicals Co., Ltd. (JP) | 2005-06-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060161003-A1 | Process for producing oxycarbonyl-substituted piperazine derivative | DHPS, AQP4, OGFOD1 | GAA 2611/4885REN 2165/4885HRH4 2943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.